NCT03482505

Brief Summary

The objective of this clinical investigational study is to compare the acoustic respiration rates (RRa) obtained using the INVSENSOR0004 sensor in the subjects up to 10 kg with the respiration rates determined by manual annotations (RRref), and when applicable with capnography respiration rate (RRcap).

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 12, 2018

Completed
11 days until next milestone

First Submitted

Initial submission to the registry

March 23, 2018

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 29, 2018

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2018

Completed
3.2 years until next milestone

Results Posted

Study results publicly available

November 15, 2021

Completed
Last Updated

November 15, 2021

Status Verified

October 1, 2021

Enrollment Period

6 months

First QC Date

March 23, 2018

Results QC Date

August 25, 2021

Last Update Submit

October 15, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Accuracy of Acoustic Respiration Rate (RRa)

    Acoustic respiration rate (RRa) as determined by the INVSENSOR00004 will be compared to measurements of actual respiration rates as determined by manual annotation of recorded respiration waveform (RRref) data. Evaluation of the RRa measurements will be reported as bias between the RRa and the RRref.

    One study visit lasting up to 60 minutes.

Study Arms (1)

INVSENSOR00004

EXPERIMENTAL

All enrolled subjects will receive the INVSENSOR00004 sensor. The INVSENSOR00004 rainbow acoustic monitoring (RAM) acoustic respiration sensor is designed to noninvasively convert acoustical airflow patterns into respiratory rate (RRa).

Device: INVSENSOR00004

Interventions

The INVSENSOR00004 will be placed on the subject's neck or chest to provide acoustic respiration rate.

INVSENSOR00004

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Subjects weighing up to 10kg
  • Subjects will be inpatients and/or outpatients admitted to the NICU (Neonatal Intensive Care Unit) or PICU (Pediatric Intensive Care Unit) or PACU (Post-Anaesthesia Care Unit)
  • The parent/legal guardian has given written informed consent/assent to participate in the study.

You may not qualify if:

  • Subjects with underdeveloped skin
  • Subjects with skin abnormalities at the planned application sites that may interfere with sensor application, per directions-for-use (DFU) or trans-illumination of the site, such as burns, scar tissue, infections, abnormalities, etc.
  • Subjects deemed not suitable for the study at the discretion of the investigator.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Loma Linda University Medical Center

Loma Linda, California, 92354, United States

Location

Children's Medical Center Dallas

Dallas, Texas, 75235, United States

Location

Results Point of Contact

Title
Cristina Johnson
Organization
Masimo

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
GT60
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 23, 2018

First Posted

March 29, 2018

Study Start

March 12, 2018

Primary Completion

August 31, 2018

Study Completion

August 31, 2018

Last Updated

November 15, 2021

Results First Posted

November 15, 2021

Record last verified: 2021-10

Data Sharing

IPD Sharing
Will not share

Locations