NCT03479515

Brief Summary

The overall objective of the proposal is to evaluate the ability of ultrasound to predict the body composition of toddlers in the outpatient clinical setting and to evaluate the relationship between body composition and neurodevelopment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jul 2018

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 12, 2018

Completed
15 days until next milestone

First Posted

Study publicly available on registry

March 27, 2018

Completed
4 months until next milestone

Study Start

First participant enrolled

July 20, 2018

Completed
4.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 6, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 6, 2023

Completed
Last Updated

February 19, 2025

Status Verified

February 1, 2025

Enrollment Period

4.9 years

First QC Date

March 12, 2018

Last Update Submit

February 18, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Ultrasound Measurements

    Tissue thickness (adipose and muscle) will be measured in cm using the ultrasound probe.

    through study completion, up to 2 years

Secondary Outcomes (3)

  • Body Composition Measurements

    through study completion, up to 2 years

  • Neurodevelopmental Status for 2 year olds

    through study completion, up to 2 years

  • Neurodevelopmental Status for 3 and 4 year olds

    through study completion, up to 2 years

Study Arms (1)

Formerly-Premature Toddlers

Data will be used to create and evaluate predictive equation

Device: Ultrasound

Interventions

Ultrasound, ADP, bioimpedance measurements

Formerly-Premature Toddlers

Eligibility Criteria

Age2 Years - 4 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Toddlers who were ≤ 36 weeks gestational age (GA) at birth who attend the University of Minnesota Masonic Children's Hospital NICU Follow Up Clinic

You may qualify if:

  • toddlers who were ≤ 36 weeks gestational age (GA) at birth who attend the University of Minnesota Masonic Children's Hospital NICU Follow Up Clinic
  • written consent obtained from a parent before or at time of visit

You may not qualify if:

  • toddlers who require medical support that prevents them from having ADP measurements taken
  • those with an inability to sit in a supported seat for 5 minutes
  • those weighing less than 10 kg

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Minnesota Masonic Children's Hospital

Minneapolis, Minnesota, 55455, United States

Location

MeSH Terms

Conditions

Premature Birth

Interventions

Ultrasonography

Condition Hierarchy (Ancestors)

Obstetric Labor, PrematureObstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital Diseases

Intervention Hierarchy (Ancestors)

Diagnostic ImagingDiagnostic Techniques and ProceduresDiagnosis

Study Officials

  • Sara Ramel, MD

    University of Minnesota

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 12, 2018

First Posted

March 27, 2018

Study Start

July 20, 2018

Primary Completion

June 6, 2023

Study Completion

June 6, 2023

Last Updated

February 19, 2025

Record last verified: 2025-02

Data Sharing

IPD Sharing
Will not share

Locations