Intraabdominal Hypertension After Kidney Transplantation
KITIV
1 other identifier
observational
100
1 country
1
Brief Summary
Intraabdominal hypertension (IAH) is a frequent and severe condition affecting intensive care patients. Gold standard for estimation of intraabdominal pressure is intravesical pressure (IVP) measurement. IVP measurement is recommended in patients presenting IAH risk factor(s). Acute kidney injury is the most frequent and described complication of IAH condition. Patients undergoing kidney transplantation have several risk factors to develop IAH. Nevertheless, to our knowledge, IAH incidence, associated factors and impact on renal function recovery remains unknown. We aim to study IAH incidence, associated factors and impact on renal function recovery in post kidney transplantation period.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started May 2017
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 8, 2017
CompletedFirst Submitted
Initial submission to the registry
February 1, 2018
CompletedFirst Posted
Study publicly available on registry
March 27, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 8, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
November 8, 2019
CompletedMarch 27, 2018
February 1, 2018
2 years
February 1, 2018
March 23, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Intraabdominal hypertension Intraabdominal pressure
Intraabdominal pressure equal or more than 12 mmHg for at least 2 measures spaced less than 24 hours. Intraabdominal pressure will be evaluated every 8 hours during the 5 days after transplantation, using UnometerTM AbdopressureTM system
day 5
Study Arms (1)
Patients
Eligibility Criteria
Patients with chronic kidney disease undergoing kidney transplantation in University Hospital of Reims (France)
You may qualify if:
- End stage chronic kidney disease ;
- Hospitalized in intensive care of nephrology unit in University Hospital of Reims (France) during study period ;
- Undergoing kidney transplantation ;
- Accepting to participate.
You may not qualify if:
- Minor ;
- Protected by the law.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- CHU de Reimslead
Study Sites (1)
Damien JOLLY
Reims, France
Related Publications (1)
Dupont V, Debrumetz A, Leguillou A, Morland D, Wynckel A, Colosio C, Mokri L, Schvartz B, Vuiblet V, Larre S, Barbe C, Rieu P. Intra-abdominal hypertension in early post-kidney transplantation period is associated with impaired graft function. Nephrol Dial Transplant. 2020 Sep 1;35(9):1619-1628. doi: 10.1093/ndt/gfaa104.
PMID: 32678426DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 1, 2018
First Posted
March 27, 2018
Study Start
May 8, 2017
Primary Completion
May 8, 2019
Study Completion
November 8, 2019
Last Updated
March 27, 2018
Record last verified: 2018-02