NCT03477695

Brief Summary

A stooped posture is one of the characteristic motor symptoms of patients with Parkinson's disease, and has been linked to impairments in ADL and QOL. We aimed to test the efficacy, safety, practical utility and user-friendliness of a posture correction and vibrotactile trunk angle feedback device (the UpRight) in the home setting of patients with Parkinson's disease with a stooped posture.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2018

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 20, 2018

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 26, 2018

Completed
6 days until next milestone

Study Start

First participant enrolled

April 1, 2018

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2019

Completed
Last Updated

May 8, 2018

Status Verified

March 1, 2018

Enrollment Period

1.8 years

First QC Date

March 20, 2018

Last Update Submit

May 6, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Average trunk angle in the sagittal plane using a Postural Analysis Chart

    Postural Analysis

    8 weeks

Secondary Outcomes (1)

  • Patient satisfaction by VAS scores

    8 weeks

Study Arms (1)

Upright device

EXPERIMENTAL

Ambulatory use of the Upright device

Device: ambulatory use of the Upright device

Interventions

Patients will wear the UpRight for a period of two month

Upright device

Eligibility Criteria

Age50 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosis of Parkinson's disease, as defined in the UK Brain Bank criteria
  • Hoehn and Yahr stage I-III
  • Participants who are at stable medication regimen
  • Able to walk independently for at least 5 minutes with or without support of accessory device.

You may not qualify if:

  • \. Mini Mental State Exam (MMSE) score\< 24

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Laboratory for gait and neurodynamics, Tel-Aviv Sourasky Medical Center

Tel Aviv, 64239, Israel

RECRUITING

Related Publications (1)

  • van Wegen EEH, de Goede CJT, Kwakkel G, van Kordelaar J. Sensor assisted self-management in Parkinson's disease: A feasibility study of ambulatory posture detection and feedback to treat stooped posture. Parkinsonism Relat Disord. 2018 Jan;46 Suppl 1:S57-S61. doi: 10.1016/j.parkreldis.2017.07.024. Epub 2017 Jul 25.

    PMID: 28802759BACKGROUND

MeSH Terms

Conditions

Parkinson DiseaseParkinsonian Disorders

Condition Hierarchy (Ancestors)

Basal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesMovement DisordersSynucleinopathiesNeurodegenerative Diseases

Study Officials

  • Nir Giladi, MD

    TASMC

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 20, 2018

First Posted

March 26, 2018

Study Start

April 1, 2018

Primary Completion

December 31, 2019

Study Completion

December 31, 2019

Last Updated

May 8, 2018

Record last verified: 2018-03

Locations