NCT03477240

Brief Summary

Cross-sectional Feasibility study on all consecutive patients of locally advanced cancer of the cervix or vault treated entirely at Tata Memorial Centre with curative intent radiation or chemoradiation.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2018

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 11, 2018

Completed
2 months until next milestone

First Posted

Study publicly available on registry

March 26, 2018

Completed
1 month until next milestone

Study Start

First participant enrolled

May 1, 2018

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2019

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2019

Completed
Last Updated

March 26, 2018

Status Verified

February 1, 2018

Enrollment Period

10 months

First QC Date

January 11, 2018

Last Update Submit

March 23, 2018

Conditions

Keywords

Cervical CancerTELEPHONIC QUESTIONNAIREFollow up

Outcome Measures

Primary Outcomes (1)

  • Accuracy of nurse-led telephonic interview for disease recurrence

    To estimate the accuracy of nurse-led telephonic interview in identifying patients with symptoms suggestive of disease recurrence, in terms of sensitivity and specificity values

    1 YEAR

Secondary Outcomes (2)

  • Accuracy of nurse-led telephonic interview for late toxicity of treatment

    1 YEAR

  • Acceptability of a nurse-led telephonic surveillance program using structured format (Form C).

    1 YEAR

Eligibility Criteria

Sexfemale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

All consecutive patients of locally advanced cancer of the cervix or vault treated entirely at Tata Memorial Centre with curative intent radiation or chemoradiation.

You may qualify if:

  • Cervical Cancer Stage Ib2, II and III (Squamous carcinoma or adenocarcinoma)
  • Cancer of the vault
  • Cancer of the cervix which inadvertently underwent hysterectomy (inadequate surgery)
  • Treated with curative intent with radical radio(chemo)therapy or NACT followed by radical radio(chemo)therapy and completed all curative treatment.
  • Within 2 years post completion of treatment
  • Has complete clinical response at 3 months post treatment
  • Informed consent
  • Contactable by telephone

You may not qualify if:

  • Patients with Stage III disease treated with palliative intent with once monthly radiotherapy
  • Early stage cervical cancer patients who underwent Wertheims hysterectomy and who have completed adjuvant radiochemotherapy due to high-risk factors
  • Metastatic cervical cancers
  • Patients who are unable to comprehend the questions or dialogue over telephone by medical staff.
  • Patients who seem unreliable for follow up

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Uterine Cervical Neoplasms

Condition Hierarchy (Ancestors)

Uterine NeoplasmsGenital Neoplasms, FemaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsUterine Cervical DiseasesUterine DiseasesGenital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor Dr.

Study Record Dates

First Submitted

January 11, 2018

First Posted

March 26, 2018

Study Start

May 1, 2018

Primary Completion

February 28, 2019

Study Completion

August 1, 2019

Last Updated

March 26, 2018

Record last verified: 2018-02

Data Sharing

IPD Sharing
Will not share

No IPD will be shared