NCT03474835

Brief Summary

The purpose of the study: to increase the efficiency of diagnosis, treatment and prediction of the course of coronary heart disease in patients with adenocarcinoma of the prostate gland, depending on the hormonal status by determining the cardiovascular risk factors, factors of angiogenesis, structural and functional state of the heart, coronary vessels, kidney damage and their pharmacological correction.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2018

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 15, 2018

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 28, 2018

Completed
23 days until next milestone

First Posted

Study publicly available on registry

March 23, 2018

Completed
23 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 15, 2018

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 15, 2019

Completed
Last Updated

March 23, 2018

Status Verified

March 1, 2018

Enrollment Period

3 months

First QC Date

February 28, 2018

Last Update Submit

March 21, 2018

Conditions

Keywords

atherosclerosisangiogenesiscardiooncology

Outcome Measures

Primary Outcomes (1)

  • cardiovascular events

    cardiovascular events development - myocardial infarction, stroke

    1 year

Study Arms (2)

ISCHEMIC HEART DISEASE and PROSTATE ADENOCARCINOMA

OTHER
Diagnostic Test: ISCHEMIC HEART DISEASE diagnostic

ISCHEMIC HEART DISEASE and PROSTATE hyperplasia

NO INTERVENTION

Interventions

ISCHEMIC HEART DISEASE diagnostic

ISCHEMIC HEART DISEASE and PROSTATE ADENOCARCINOMA

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • men aged 45-75 years
  • presence of verified diagnosis of adenocarcinoma of the prostate gland,
  • stable antitumor therapy for 6 months, verified diagnosis of CAD,
  • stable cardiological therapy for the past 3 months,
  • voluntary informed consent to participate in the study.

You may not qualify if:

  • age older than 75 years,
  • female sex,
  • metastatic lesion,
  • chronic heart failure of the III-IV functional class (FC),
  • arrhythmias that cause hemodynamic impairment and require antiarrhythmic correction (including ventricular arrhythmias of high gradation, atrial flutter , paroxysmal tachycardia, sinus node weakness syndrome, 2-3-degree AV block),
  • AMI, acute cerebrovascular accident,
  • diabetes mellitus (insulin-dependent diabetes mellitus) with a level of NvA1s\> 7%, hyperthyroidism and hypothyroidism level of TSH\> 10 mD / L, chronic renal failure (GFR \<30 ml / min / 1.73 m2),
  • acute cardiac and renal insufficiency,
  • obesity 4 degrees,
  • cachexia.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

SE Dnipropetrovsk medical academy

Dnipro, Ukraine

Location

MeSH Terms

Conditions

Myocardial IschemiaAtherosclerosis

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesVascular DiseasesArteriosclerosisArterial Occlusive Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
professor assistant

Study Record Dates

First Submitted

February 28, 2018

First Posted

March 23, 2018

Study Start

January 15, 2018

Primary Completion

April 15, 2018

Study Completion

January 15, 2019

Last Updated

March 23, 2018

Record last verified: 2018-03

Locations