Seoul National University Pituitary Disease Cohort Study
SNU-PIT
1 other identifier
observational
1,600
1 country
1
Brief Summary
The purpose of this study is to investigate the treatment and natural history of pituitary disease. We have a longstanding interest in pituitary disease including acromegaly, central diabetes insipidus, and nonfunctioning pituitary adenoma. We will continue to follow patients and recruit new patients for treatment and follow-up. Blood and pituitary tumor tissue (when available through clinical care) will be saved for future analyses related to pituitary disease.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2015
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 15, 2015
CompletedFirst Submitted
Initial submission to the registry
March 10, 2018
CompletedFirst Posted
Study publicly available on registry
March 22, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 14, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
February 14, 2025
CompletedMarch 18, 2020
March 1, 2019
9.9 years
March 10, 2018
March 17, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Treatment outcome of pituitary diseases
Remission rate
Up to 10 years
Secondary Outcomes (1)
Complications of pituitary disease
Up to 10 years
Study Arms (8)
Acromegaly
Patients diagnosed with acromegaly
Cushing's disease
Patients diagnosed with Cushing's disease
Hyperprolactinemia/prolactinomas
Patients diagnosed with hyperprolactinemia/prolactinoma
Pituitary stalk lesions
Patients diagnosed with pituitary stalk lesions
Nonfunctioning pituitary adenomas
Patients diagnosed with nonfunctioning pituitary adenomas
Central diabetes insipidus
Patients diagnosed with central diabetes insipidus
Craniopharyngioma
Patients diagnosed with craniopharyngiomas
Others
Patients diagnosed with other suprasellar/parasellar lesions
Interventions
1. Medical history 2. Imaging examination including brain magnetic resonance imaging 3. Blood (Basal hormone study and follow-up study) and pituitary tumor tissue
Eligibility Criteria
Patients diagnosed with pituitary disease at Seoul National University Hospital
You may qualify if:
- Subjects for this study will be recruited if they are:
- Adults, male or female aged 18 years or older
- diagnosed with pituitary diseases such as acromegaly, Cushing's disease, hyperprolactinemia, nonfunctioning pituitary adenoma, pituitary stalk lesions, central diabetes insipidus, and craniopharyngiomas
You may not qualify if:
- Patients who do not agree with the study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Seoul National University Hospital
Seoul, 03080, South Korea
Biospecimen
Blood Pituitary tumor tissue
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jung Hee Kim, M.D
Seoul National University Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
March 10, 2018
First Posted
March 22, 2018
Study Start
March 15, 2015
Primary Completion
February 14, 2025
Study Completion
February 14, 2025
Last Updated
March 18, 2020
Record last verified: 2019-03
Data Sharing
- IPD Sharing
- Will not share