The Incidence of Aphasia, Dysarthria and Dysphagia Following Stroke

NCT03472625 | Completed

• 1 other identifier: B670201835160
• Study Type: observational
• Target: 557
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of the study is to estimate the incidence and recovery of aphasia, dysarthria and dysphagia in an acute setting (first week) with the NIHSS sub-item scores for language and speech and a dysphagia screening. Furthermore, we will evaluate the severity of aphasia, dysarthria and dysphagia in an acute setting (first few days) with standardized measurements (ScreeLing, BNT, NSVO-Z, perceptual assessment, MASA/FOIS). To evaluate the effect of early IVT/EVT in patients with ischemic stroke on functional outcomes for language and speech via the NIHSS scale.

Conditions

Acute Stroke

Outcome Measures

Primary Outcomes (1)

• Incidence of aphasia

  Incidence is based on the National Institute for Health Stroke Scale (NIHSS), subscale 9. The NIHSS is used to quantify the impairment in patients after stroke. For the incidence of aphasia, subscale 9 of the NIHSS scale is used (best language). It investigates whether a patient has aphasia and what degree if present. Scores on this subscale range from 0 (= normal) to 3 (= mute/global aphasia)

  3 days

Secondary Outcomes (10)

• Incidence of dysarthria

  3 days

• Incidence of dysphagia

  3 days

• Severity of aphasia (screening test)

  3 days

• Severity of aphasia (naming test)

  3 days

• severity of dysarthria (perceptual assessment)

  3 days

Study Arms (1)

Acute stroke patients

All acute stroke patients will be screened for aphasia, dysarthria or dysphagia. When one of the symptoms is present, standardized assessments will follow to evaluate the severity. Recovery in time will be measured +/- 1 week following stroke.

Diagnostic Test: Screening and diagnosis of aphasia, dysarthria, dysphagia

Interventions

Screening and diagnosis of aphasia, dysarthria, dysphagia DIAGNOSTIC_TEST

Screening (day 2 +/- 1; day 7 +/-1): NIHSS (National Health Institute Scale) 9 and 10 scores, dysphagia screening (nurse), speech-, and language screening (speech therapist) Diagnostic assessment (day 2 +/-1-): Dysphagia: MASA (Mann Assessment of Swallowing Abilities), FOIS (Functional Oral Intake Scale) Dysarthria: perceptual assessment, NSVO-Z (Nederlands spraakverstaanbaarheidsonderzoek - zinnen) Aphasia: ScreeLing, BNT (Boston Naming Test)

Acute stroke patients

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients recruited at the Acute Stroke Unit (university hospital Ghent)

You may qualify if:

• Acute stroke patients admitted at the Acute Stroke Unit at the university hospital (Ghent)

You may not qualify if:

• Previous aphasia, dysarthria, dysphagia

Sponsors & Collaborators

• University Hospital, Ghent: lead

Study Sites (1)

University Hospital, department of neurology

Ghent, East-Flanders, 9000, Belgium

Location

Related Publications (1)

• De Cock E, Batens K, Hemelsoet D, Boon P, Oostra K, De Herdt V. Dysphagia, dysarthria and aphasia following a first acute ischaemic stroke: incidence and associated factors. Eur J Neurol. 2020 Oct;27(10):2014-2021. doi: 10.1111/ene.14385. Epub 2020 Jun 30.

  PMID: 32515514 DERIVED

MeSH Terms

Conditions

Stroke

Interventions

Mass Screening

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Diagnostic Techniques and Procedures; Diagnosis; Health Surveys; Surveys and Questionnaires; Data Collection; Epidemiologic Methods; Investigative Techniques; Diagnostic Services; Preventive Health Services; Health Services; Health Care Facilities Workforce and Services; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health; Public Health Practice

Study Officials

• veerle De Herdt

  University Ghent

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 5, 2018
• First Posted: March 21, 2018
• Study Start: March 14, 2018
• Primary Completion: October 4, 2019
• Study Completion: October 4, 2019
• Last Updated: September 19, 2024

Record last verified: 2024-09

Locations

BE (1)