NCT03470493

Brief Summary

This study compares the diagnostic capability of a home sleep apnea testing device to polysomnography.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
130

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Apr 2018

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 28, 2018

Completed
20 days until next milestone

First Posted

Study publicly available on registry

March 20, 2018

Completed
22 days until next milestone

Study Start

First participant enrolled

April 11, 2018

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 6, 2019

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2019

Completed
1.8 years until next milestone

Results Posted

Study results publicly available

May 20, 2021

Completed
Last Updated

May 20, 2021

Status Verified

April 1, 2021

Enrollment Period

11 months

First QC Date

February 28, 2018

Results QC Date

March 23, 2021

Last Update Submit

April 28, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Diagnostic Sensitivity of Apnealink (AL) Compared With Polysomnography (PSG)

    The Respiratory Event Index (REI) provided by the AL will be compared with the REI provided by the PSG test. REI will be scored according to American Academy of Sleep Medicine (AASM) 2012 guidelines. The REI provided by the AL for each participant is divided by the REI provided by the PSG for the same participant to get the diagnostic sensitivity of the Apnealink.

    Day 1

Secondary Outcomes (3)

  • Diagnostic Sensitivity of Apnealink (AL) Compared With Polysomnography (PSG) to Identify Obstructive Events

    Day 1

  • Diagnostic Sensitivity of the AL to Determine Central Events Compared With PSG

    Day 1

  • Positive Likelihood Ratio of Apnealink Air

    Day 1

Study Arms (1)

Participants

EXPERIMENTAL

ApneaLink Air

Diagnostic Test: ApneaLink Air

Interventions

ApneaLink AirDIAGNOSTIC_TEST

ApneaLink Air to be used on each participant undergoing PSG

Participants

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Participant is 18 years of age or older
  • Participant is willing to provide informed consent
  • Participant is willing to participate in all study related procedures

You may not qualify if:

  • Unable to cease positive airway pressure (PAP) therapy during PSG (if currently using)
  • Requires use of oxygen therapy during sleep
  • Diagnosis of uncontrolled clinically relevant sleep disorder (e.g., untreated insomnia or restless leg syndrome)
  • Pregnant
  • Participant is unsuitable to participate in the study in the opinion of the investigator

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

University of Florida

Gainesville, Florida, 32611, United States

Location

University of Miami

Miami, Florida, 33136, United States

Location

MeSH Terms

Conditions

Sleep Apnea Syndromes

Condition Hierarchy (Ancestors)

ApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Results Point of Contact

Title
Adam Benjafield
Organization
ResMed

Study Officials

  • Richard Berry, MD

    University of Florida

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 28, 2018

First Posted

March 20, 2018

Study Start

April 11, 2018

Primary Completion

March 6, 2019

Study Completion

July 31, 2019

Last Updated

May 20, 2021

Results First Posted

May 20, 2021

Record last verified: 2021-04

Data Sharing

IPD Sharing
Will not share

Locations