Anesthetic Cost Analysis With Desflurane in Automated Gas Control Mode

NCT03465475 | Completed

• 1 other identifier: Inonu uni
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Inhalation agents constitute the major part of anesthetic drug costs (20% - 25%) and a significant portion of the applied inhalation agents are thrown into the atmosphere through the waste gas system without being absorbed by the patient. The amount of waste gas is directly correlated to the fresh gas flow (FGF). Reducing the TGA during general anesthesia reduces the consumption of inhalant agents and contributes to the reduction of greenhouse gas pollution. Risks such as hypoxia, hypercapnia, inadequate depth of anesthesia and potential toxic gas accumulation were associated with low flow anesthesia, but the patient was provided with adequate safety by following pulse oximetry, capnography, FiO2 and anesthetic gas analysis. We aimed to perform anesthetic cost analysis and patient security in automated gas control mode (AGC).

Conditions

Safety Issues

Keywords

Low flow anesthesia; Desflurane; Cost analysis; Automated gas control

Outcome Measures

Primary Outcomes (1)

• Amount of used anesthetic gas (desflurane)

  Amount of used desflurane will be determined in milliliter by anesthesia machine (Maquet Flow i40) for each patient.

  Through study completion, an average of 2 month

Secondary Outcomes (3)

• Heart rate

  Through study completion, an average of 2 month

• Mean arterial pressure

  Through study completion, an average of 2 month

• Peripheral oxygen saturation

  Through study completion, an average of 2 month

Study Arms (3)

Group 1

The patient who receive 300 mL fresh gas flow with AGC mode during the general anesthesia

Group 2

The patient who receive 600 mL fresh gas flow with AGC mode during the general anesthesia

Group 3

The patient who receive 600 mL fresh gas flow with manuelly during the general anesthesia

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients undergoing hepatectomy operation

You may qualify if:

• Adult patients undergoing hepatectomy with general anesthesia

You may not qualify if:

• Essential data missing
• Patient participating in other research projects
• Drug allergy
• Anesthetic complication story

Sponsors & Collaborators

• Inonu University: lead

Study Sites (1)

Inonu Univercity

Malatya, 44280, Turkey (Türkiye)

Location

Study Officials

• Yusuf Z Çolak, MD

  Investigator

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: February 1, 2018
• First Posted: March 14, 2018
• Study Start: July 1, 2018
• Primary Completion: October 30, 2020
• Study Completion: March 1, 2021
• Last Updated: August 25, 2021

Record last verified: 2021-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)