NCT03465150

Brief Summary

With 24 million results associated with Google's searchon keywords "severe acne", Pr Dreno's team understand better thatthis disease, which affects many French people, is a real concern of Public Health and not a "forced evil" of the adolescent period, which will eventually resolve itself. Acne does not affect the vital prognosis, but its psychosocial impact is major and should not be underestimated. Paradoxically, despite the high prevalence of acne, few quality epidemiological studies have been published. Physicians are often helpless when faced with patients' questions. They often need a lot of explanations, especially on the factors aggravating this dermatosis, which greatly affects their quality of life. This cohort, the first of its kind in France, will determine the predictive factors of therapeutic response, endogenous and environmental factors impacting on the severity of acne assess the quality of life and psychological impact of acne patients, determine the patient's course of care and the associated costs. Pr Dreno's team will also build up a bio collection (bacteriological samples).

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
93mo left

Started Sep 2018

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress50%
Sep 2018Dec 2033

First Submitted

Initial submission to the registry

February 5, 2018

Completed
1 month until next milestone

First Posted

Study publicly available on registry

March 14, 2018

Completed
6 months until next milestone

Study Start

First participant enrolled

September 23, 2018

Completed
14.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2033

Expected
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 28, 2033

Last Updated

April 13, 2026

Status Verified

April 1, 2026

Enrollment Period

14.4 years

First QC Date

February 5, 2018

Last Update Submit

April 7, 2026

Conditions

Keywords

AcneCohortprospectiverisk factors

Outcome Measures

Primary Outcomes (1)

  • Measure of Acne stage

    composite criteria. the scale is GEA for Global Evaluation Acne Scale with 0 no acne to 5 severe acne

    2 years

Secondary Outcomes (3)

  • assessing patients' quality of life

    2 years

  • cost of acne illness

    2 years

  • Bacteriological sample to find Propionibacterium acnes, Hormonal check-up on blood sample

    2 years

Interventions

acneOTHER

Patient with acne

Also known as: acne vulgaris

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients going for the first time in specialized consultation "acne"

You may qualify if:

  • Patient with acne
  • Patient (or parents/guardians for minors) who are not opposed to participating in the cohort.
  • Subjects affiliated to an appropriate health insurance

You may not qualify if:

  • Dermatosis of the face other than acne
  • Refusal to participate by the minor or parent/guardian
  • Adults under a legal protection regime (guardianship, trusteeship, judicial safeguard)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU de Nantes

Nantes, 44000, France

RECRUITING

MeSH Terms

Conditions

Acne Vulgaris

Interventions

Acne RA-1,2

Condition Hierarchy (Ancestors)

Acneiform EruptionsSkin DiseasesSkin and Connective Tissue DiseasesSebaceous Gland Diseases

Study Officials

  • Brigitte DRENO, PU-PH

    Nantes University Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
2 Years
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 5, 2018

First Posted

March 14, 2018

Study Start

September 23, 2018

Primary Completion (Estimated)

February 28, 2033

Study Completion (Estimated)

December 28, 2033

Last Updated

April 13, 2026

Record last verified: 2026-04

Locations