NCT03463603

Brief Summary

When doctors and nurses use accepted guidelines for quickly treating patients who come to the emergency department (ED) with a possible heart attack, patients do better. Research shows that there are racial-identity- and ethnicity-based differences in the symptoms these patients have, when and why they seek care, the treatments they receive, and how well they fare afterwards. There is also Canadian evidence that there may be racial-identity-based disparities in the care some patients receive, and it has been suggested that health professionals may unconsciously treat patients of different racial identities differently. But it is not known if there is racial-identity variation in the care given to Canadian patients with heart attack symptoms in the critical first hours after coming to an ED, or in their experiences of this care. The investigators collected information from the health records of patients who come to EDs with symptoms of heart attack. The investigators recorded events and times such as what provisional diagnosis was assigned to the patient, how often they received pain medication, how long until certain tests were performed and what treatments were offered. The investigators also collected information about things that might affect delivery of care, e.g., the number of doctors and nurses who were on duty. Participants also completed a short questionnaire about their reasons for coming to the hospital, how long they waited before coming and why, and what their experience in the ED was like. The investigators reviewed this information to see if there are racial-identity-based differences in the care received by patients with heart attack symptoms. The findings could identify important disparities, which could in turn inform future projects to correct these disparities, for example, education of health professionals about ethnic differences in ideas of health and illness.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
448

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2013

Typical duration for all trials

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 7, 2013

Completed
3.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 11, 2017

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 12, 2017

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

February 5, 2018

Completed
1 month until next milestone

First Posted

Study publicly available on registry

March 13, 2018

Completed
Last Updated

March 14, 2018

Status Verified

March 1, 2018

Enrollment Period

3.3 years

First QC Date

February 5, 2018

Last Update Submit

March 12, 2018

Conditions

Keywords

ischemic heart diseaseacute coronary syndromeracial bias

Outcome Measures

Primary Outcomes (1)

  • Door to ECG

    time from Emergency triage to first ECG acquisition

    from hour and minute of admission until the hour and minute of first documented ECG, up to 48 hours

Secondary Outcomes (4)

  • Number of assessments by health professionals

    from hour and minute of admission until the hour and minute of transfer to inpatient unit or discharge from Emergency Department, whichever comes first, up to 48 hours

  • Rate of being offered and consenting to coronary angiogram

    from date of admission until the date of hospital discharge, up to 100 weeks

  • Rate of being offered and consenting to any revascularization procedure

    from date of admission until the date of hospital discharge, up to 24 weeks

  • ethnic differences in treatment-seeking delay

    from hour and minute of first documented symptoms until the hour and minute of first documented help-seeking, up to 168 hours

Study Arms (3)

Asian racial identity

Those who self-report "Asian" or related terms as their racial identity.

South Asian racial identity

Those who self-report "South Asian" or related terms as their racial identity.

Other racial identity

All others, who self-report neither "Asian", "South Asian" or their related terms as their racial identity.

Eligibility Criteria

Age20 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients presenting to Emergency Departments with symptoms suggestive of an acute coronary syndrome.

You may qualify if:

  • years of age or older
  • presented to the ED and are either referred for immediate cardiology consultation or managed according to a standardized protocol for continued observation and referral for follow-up (whether ultimately admitted or not);
  • hemodynamically stable and free of ischemic discomfort for at least one hour
  • spoke English, Mandarin, Cantonese, Punjabi
  • able to provide informed consent.

You may not qualify if:

  • being cared for by any of the Emergency physicians (3) who were co-investigators

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Richmond Hospital

Richmond, British Columbia, V6X 1A2, Canada

Location

Surrey Memorial Hospital

Surrey, British Columbia, V3V 1Z2, Canada

Location

St. Paul's Hospital

Vancouver, British Columbia, V6Z1Y6, Canada

Location

Related Publications (2)

  • Iacoe E, Ratner PA, Wong ST, Mackay MH. A cross-sectional study of ethnicity-based differences in treatment seeking for symptoms of acute coronary syndrome. Eur J Cardiovasc Nurs. 2018 Apr;17(4):297-304. doi: 10.1177/1474515117741893. Epub 2017 Nov 15.

  • Mackay, M.H., Ratner, P.A., Scheuermeyer, F.X., Veenstra, G., Ramanathan, K.R., O'Sullivan, M.E., Grubisic, M., Murray, C., Humphries, K.H. (2017). Is racism a factor in emergency department care of patients with suspected acute coronary syndrome? Canadian Journal of Cardiology, 33 (10), s125-126.

    RESULT

MeSH Terms

Conditions

Acute Coronary SyndromeRacismMyocardial Ischemia

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesVascular DiseasesPrejudiceSocial BehaviorBehaviorSocial Discrimination

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical Associate Professor

Study Record Dates

First Submitted

February 5, 2018

First Posted

March 13, 2018

Study Start

October 7, 2013

Primary Completion

January 11, 2017

Study Completion

April 12, 2017

Last Updated

March 14, 2018

Record last verified: 2018-03

Locations