NCT03456869

Brief Summary

The purpose of this study is to assess the accuracy and clinical validation of patient specific implants (PSI) technique for genioplasty.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2015

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2015

Completed
2.3 years until next milestone

First Submitted

Initial submission to the registry

February 5, 2018

Completed
1 month until next milestone

First Posted

Study publicly available on registry

March 7, 2018

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2019

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2019

Completed
Last Updated

March 7, 2018

Status Verified

February 1, 2018

Enrollment Period

4 years

First QC Date

February 5, 2018

Last Update Submit

February 28, 2018

Conditions

Keywords

patient specific implantcomputer-aided surgeryclinical accuracy

Outcome Measures

Primary Outcomes (2)

  • Positional differences of the chin between the plan and postoperative results

    The coordinates of the centroid of three land points on the chin segment was used to calculate the position differences between the plan and postoperative results in X, Y and Z axis.

    2 weeks after the operation

  • Orientation differences of the chin between the plan and postoperative results

    The coordinates of three independent points were used to define the orientation of the chin in 3D space. The orientation differences were calculated in pitch (the rotation around the X axis), roll (the rotation around the Y axis), and yaw (the rotation around the Z axis).

    2 weeks after the operation

Secondary Outcomes (2)

  • time consuming

    3 days after the operation

  • economic consuming

    3 days after the operation

Study Arms (1)

PSI group

EXPERIMENTAL

The patient specific implant (PSI) is used to completed the genioplasty.

Device: Patient Specific Implant

Interventions

The patient specific implant is used to simultaneously complete the reposition and fixation of the chin.

PSI group

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • patients who were scheduled to undergo genioplasty;
  • patients who were scheduled to undergo CT scan as a part of their diagnosis and treatment;
  • patients who agreed to participate in this study

You may not qualify if:

  • craniofacial syndrome;
  • segmental osseous genioplasty;
  • previous osseous genioplasty;
  • previous mandibular trauma;
  • systemic disorders.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ninth People's Hospital, Shanghai Jiaotong University School of Medicine

Shanghai, China

RECRUITING

Central Study Contacts

Biao Li, Master

CONTACT

Xudong Wang, Doctor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Acting chair of Department of Oral and Craniomaxillofacial Surgery

Study Record Dates

First Submitted

February 5, 2018

First Posted

March 7, 2018

Study Start

November 1, 2015

Primary Completion

October 31, 2019

Study Completion

December 31, 2019

Last Updated

March 7, 2018

Record last verified: 2018-02

Locations