Factors Influencing Hemoglobin Variability and Its Association With Mortality in Hemodialysis Patients

NCT03454906 | Completed

• 1 other identifier: KA09/358
• Study Type: observational
• Target: 169
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of the study is to investigate the factors influencing hemoglobin variability with inflammatory and nutritional parameters and its associations with all-cause mortality among hemodialysis patients.

Conditions

Hemodialysis-Induced Symptom

Keywords

hemodialysis; hemoglobin variability; mortality; nutrition; inflammation

Outcome Measures

Primary Outcomes (1)

• Factors Influencing Hemoglobin Variability and Its Association with Mortality in Hemodialysis Patients

  investigation of factors influencing hemoglobin variability with inflammatory and nutritional parameters and the association of hemoglobin variability with all-cause mortality among hemodialysis patients

  six month

Study Arms (6)

L Hemoglobin

L Hemoglobin: consistently low all 6 months with low hemoglobin levels

T Hemoglobin

T Hemoglobin; consistently within the target range all 6 months with target-range hemoglobin levels

H Hemoglobin

H Hemoglobin: consistently high all 6 months with high hemoglobin levels

LAL Hemoglobin

LAL Hemoglobin: low amplitude fluctuation with low hemoglobin; all 6 months with low or target range hemoglobin levels

LAH Hemoglobin

LAH Hemoglobin: low-amplitude fluctuation with high hemoglobin levels 6 months with target-range or high hemoglobin levels)

HA Hemoglobin

HA Hemoglobin ; high-amplitude fluctuation low, target-range, and high hemoglobin levels within the 6 month period

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

-one hundred and sixty nine patient that receive chronic hemodialysis treatment in Baskent university hospital were enrolled to the study.

You may qualify if:

• Age \>18
• on chronic hemodialysis treatment

You may not qualify if:

• All patients had a minimum of six hemoglobin measurements within a 6- month period, and they were excluded if they received a kidney transplant during this period or those who had blood transfusions during the baseline period.
• Patients with serum ferritin\<100 μg/L were also excluded from the study because of reimbursement of our country.

Sponsors & Collaborators

• Baskent University: lead

Related Publications (1)

• Bal Z, Demirci BG, Karakose S, Tutal E, Erkmen Uyar M, Acar NO, Sezer S. Factors Influencing Hemoglobin Variability and Its Association with Mortality in Hemodialysis Patients. ScientificWorldJournal. 2018 Apr 1;2018:8065691. doi: 10.1155/2018/8065691. eCollection 2018.

  PMID: 29805324 DERIVED

MeSH Terms

Conditions

Inflammation

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Baskent University Nephrology Department

Study Record Dates

• First Submitted: February 2, 2018
• First Posted: March 6, 2018
• Study Start: January 1, 2009
• Primary Completion: January 1, 2010
• Study Completion: February 1, 2010
• Last Updated: March 6, 2018

Record last verified: 2018-02

Data Sharing

• IPD Sharing: Will not share