NCT03454074

Brief Summary

An accumulating body of research indicates that activities such as exercise, active cognitive and social engagement, good sleep hygiene, stress reduction and proper nutrition are associated with the maintenance of cognitive health. Emerging data also suggests that healthy lifestyle behaviors may promote brain plasticity. Despite nationwide efforts to raise public awareness about brain health, there remains a gap concerning how to best promote behavioral change and help at-risk middle-aged and older adults adopt effective, evidence-based brain health behaviors into their everyday lives to maximize cognitive health. The objective of this study is to evaluate the efficacy of a 7-week group brain fitness intervention (B-Fit) for increasing preventative brain health behaviors and enhancing cognitive health in participants at-risk for cognitive impairment. We will also examine mechanisms of action of the B-Fit intervention through tracking of behavioral responses in the real-world environment using wearable sensors.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 15, 2016

Completed
2 years until next milestone

Study Start

First participant enrolled

February 15, 2018

Completed
18 days until next milestone

First Posted

Study publicly available on registry

March 5, 2018

Completed
4.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2022

Completed
Last Updated

October 9, 2018

Status Verified

October 1, 2018

Enrollment Period

4.9 years

First QC Date

February 15, 2016

Last Update Submit

October 4, 2018

Conditions

Keywords

healthy agingbehavior changeolder adults

Outcome Measures

Primary Outcomes (2)

  • Healthy Aging Activity Engagement

    (Subjective Measure) Healthy Aging Activity Engagement Scale (HAAE): participants use a 5-point Likert scale to rate level of agreement with engagement in healthy brain behaviors during the past week from strongly disagree (0) to strongly agree (5). Scores range from 32 to 160, with higher scores representing greater engagement in positive health behaviors.

    Change in engagement in healthy brain aging behaviors as measured by the HAAE from baseline to post-test (appr. 2 months) and follow-up (appr. one-year).

  • Objective sensor-based behavior change detection with wearable sensors

    (Objective Measure) Participants will wear an Actigraph for 1 week to capture objective data in the form of activity times, activity durations, mobility, activity level and sleep/time quality. We will apply the behavior change detection approach (BCD) to detect the magnitude of health-related changes in behavior patterns and to describe the nature of the changes (e.g., increased afternoon activity).

    Change in activities captured by actigraphs and measured using a behavior change detection approach at baseline compared to post-test (appr. 2 months) and follow-up (appr. one-year).

Secondary Outcomes (4)

  • Physical Capability

    Change in mobility as measured by the SPPB from baseline to post-test (appr. 2 months) and follow-up (appr. one-year).

  • Psychological Wellbeing

    Change in psychological wellbeing as measured by the total score of the NIH Toolbox surveys from baseline to post-test (appr. 2 months) and follow-up (appr. one-year).

  • Cognitive Function

    Change in fluid cognitive abilities as measured by the NIH Toolbox fluid cognition composite from baseline to post-test (appr. 2 months) and follow-up (appr. one-year).

  • Social Wellbeing

    Change in social wellbeing as measured by the total score of the NIH surveys from baseline to post-test (appr. 2 months) and follow-up (appr. one-year).

Study Arms (3)

B-Fit intervention

EXPERIMENTAL

Combines group education about brain health with individualized goal-setting and group problem-solving to help participants effectively integrate healthy behavioral changes into their everyday lives.

Behavioral: Problem-solvingBehavioral: Education

Education Only

ACTIVE COMPARATOR

Provide group education about healthy behavior changes without problem-solving component.

Behavioral: Education

Wait-list

NO INTERVENTION

No intervention administered. Will be offered intervention following a delay.

Interventions

Problem-solvingBEHAVIORAL

Individualized goal-setting and group problem-solving to help older adults effectively integrate realistic, healthy behavioral changes into their everyday lives

B-Fit intervention
EducationBEHAVIORAL

Education about healthy brain aging behaviors provided.

B-Fit interventionEducation Only

Eligibility Criteria

Age40 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 40+ (midlife and older adults)

You may not qualify if:

  • Adults under the age of 40
  • Adults who meet criteria for dementia
  • Adults who cannot provide own informed consent
  • Adults who cannot complete assessments or participate in the intervention protocols due to vision, hearing, communication or other difficulties
  • Adults unable to read and comprehend information in English.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Washington State University

Pullman, Washington, 99164-4820, United States

RECRUITING

Related Publications (1)

  • Boyd B, McAlister C, Arrotta K, Schmitter-Edgecombe M. Self-Reported Behavior Change and Predictors of Engagement With a Multidomain Brain Health Intervention for Midlife and Older Adults: A Pilot Clinical Trial. J Aging Health. 2022 Jan;34(1):109-119. doi: 10.1177/08982643211032483. Epub 2021 Jul 15.

MeSH Terms

Conditions

Health Behavior

Interventions

Educational Status

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Socioeconomic FactorsPopulation Characteristics

Study Officials

  • Maureen Schmitter-Edgecombe, Ph.D.

    Washington State University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Maureen Schmitter-Edgecombe, Ph.D.

CONTACT

Stephanie Saltness, B.S.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 15, 2016

First Posted

March 5, 2018

Study Start

February 15, 2018

Primary Completion

December 30, 2022

Study Completion

December 30, 2022

Last Updated

October 9, 2018

Record last verified: 2018-10

Data Sharing

IPD Sharing
Will not share

Locations