NCT03444532

Brief Summary

This study of a randomized controlled trial aims to evaluate the feasibility of a 12-week sleep program and the randomized controlled trial research procedure. In total 20 participants will be recruited and randomized to the intervention or control group.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2018

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 9, 2018

Completed
14 days until next milestone

First Posted

Study publicly available on registry

February 23, 2018

Completed
7 days until next milestone

Study Start

First participant enrolled

March 2, 2018

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2019

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2019

Completed
Last Updated

May 5, 2020

Status Verified

May 1, 2020

Enrollment Period

1.1 years

First QC Date

February 9, 2018

Last Update Submit

May 4, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Sleep

    Measured by actigraphy, to investigate change in sleep from baseline to 12 weeks and the difference in change between intervention - and the control group

    Change from baseline sleep at 12 weeks

Secondary Outcomes (11)

  • Cardiorespiratory fitness

    Baseline, 12-weeks

  • Fatigue

    Baseline, 12 weeks, 6 month

  • Physical activity

    Baseline, 12 weeks, 6 month

  • Depression

    Baseline, 12 weeks, 6 month

  • Anxiety

    Baseline, 12 weeks, 6 month

  • +6 more secondary outcomes

Study Arms (2)

12-week aerobic exercise and cognitive-behavioral therapy

EXPERIMENTAL

12-week aerobic exercise, two times per week, and cognitive-behavioral therapy for insomnia in total four sessions

Behavioral: 12-week aerobic exercise and cognitive-behavioral therapy

Control group

NO INTERVENTION

Patients assigned to the control group will receive usual care

Interventions

12-week intervention of aerobic exercise training and four session of cognitive-behavioral therapy

12-week aerobic exercise and cognitive-behavioral therapy

Eligibility Criteria

Age18 Years+
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Prostate cancer
  • Receiving treatment with androgen deprivation therapy or in combination with chemotherapy
  • Insomnia
  • Over 18-yers old
  • Understand oral and written Danish
  • Written informed consent

You may not qualify if:

  • Medical assessment that does not allow aerobic exercise
  • Severe cognitive problems
  • Night work during the interventions period
  • Exercise training more than three times a week

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Oncology Department

Næstved, Denmark

Location

MeSH Terms

Conditions

Prostatic NeoplasmsSleep Initiation and Maintenance Disorders

Interventions

ExerciseCognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesMental Disorders

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological PhenomenaBehavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Christoffer Johansen, PhD, Dr.Med

    Danish Cancer Society Research Center

    PRINCIPAL INVESTIGATOR
  • Katrine Løppenthin, PhD

    Danish Cancer Society Research Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

February 9, 2018

First Posted

February 23, 2018

Study Start

March 2, 2018

Primary Completion

March 31, 2019

Study Completion

May 31, 2019

Last Updated

May 5, 2020

Record last verified: 2020-05

Locations