Phenotypes of COPD
Chronic Obstructive Pulmonary Disease Phenotypes in Non-Smokers
1 other identifier
observational
50
0 countries
N/A
Brief Summary
Chronic Obstructive Pulmonary Disease (COPD) has been defined by international guidelines as a common preventable and treatable disease characterized by persistent air flow limitation and respiratory symptoms caused by exposure to gases or noxious particles. COPD is a major cause of morbidity and mortality worldwide. It is predicted to become the third leading cause of death and the fifth leading cause of disability by the year 2020.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Apr 2019
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 22, 2018
CompletedFirst Posted
Study publicly available on registry
February 13, 2018
CompletedStudy Start
First participant enrolled
April 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2021
CompletedJune 27, 2018
June 1, 2018
1 year
January 22, 2018
June 25, 2018
Conditions
Outcome Measures
Primary Outcomes (1)
Rate of risk factors of COPD in non smokers.
Complete medical history will be taken for each patient to detect risk factors of COPD.
48 hour
Study Arms (1)
Non-smoker COPD patients
stable non-smoker COPD patients diagnosed by a previous spiromtery to have FEV1/FVC less than 70
Interventions
High resolution computed tomography scan of the chest \& pulmonary function tests will be done for every patient to classify them.
Eligibility Criteria
Non smoker COPD stable patients
You may qualify if:
- Non-smoker COPD patients.
- Stable COPD patients (≥4 weeks without exacerbation or worsening of any relevant comorbidity).
You may not qualify if:
- Patients with COPD exacerbation.
- Patients with associated obstructive sleep apnea.
- Patients with associated interstitial lung disease.
- patients with associated cardiac problems.
- Patients with associated bronchiaectasis.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (2)
Sharma BB, Singh V. Nonsmoker COPD: Is it a reality? Lung India. 2017 Mar-Apr;34(2):117-119. doi: 10.4103/lungindia.lungindia_56_17. No abstract available.
PMID: 28360456BACKGROUNDMohan A, Sharma M, Uniyal A, Borah R, Luthra K, Pandey RM, Madan K, Hadda V, Guleria R. Variability in proteinase-antiproteinase balance, nutritional status, and quality of life in stable chronic obstructive pulmonary disease due to tobacco and nontobacco etiology. Lung India. 2016 Nov-Dec;33(6):605-610. doi: 10.4103/0970-2113.192859.
PMID: 27890988BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal investigator
Study Record Dates
First Submitted
January 22, 2018
First Posted
February 13, 2018
Study Start
April 1, 2019
Primary Completion
April 1, 2020
Study Completion
April 1, 2021
Last Updated
June 27, 2018
Record last verified: 2018-06