The SALMANTICOR Study

NCT03429452 | Completed DMC

• 1 other identifier: PI14/00695
• Study Type: observational
• Target: 2,057
• Locations: 1 country
• Sites: 1

Brief Summary

The SALMANTICOR study will obtain data on the prevalence and incidence of structural heart disease in a population setting. A cross-section survey of randomly selected residents of Salamanca (Spain) will be performed. A total of approximately 2400 individuals, stratifies by place of residence (rural and urban) and by age and sex will be studied. The variables to analyzed will be obtained from the clinical history, different surveys including social status, Mediterranean diet, functional capacity, electrocardiogram, echocardiogram and biochemical and genetic analysis. Surviving participants are expected to return for a 5 and 10-year follow-up visit.

Conditions

Structural Heart Abnormality

Keywords

structural heart abnormality; spatial method; echocardiography; electrocardiogram; mediterranean diet; exercise; social status; rural

Outcome Measures

Primary Outcomes (2)

• prevalence of structural heart disease in a population setting

  Structural heart disease refers to any of the following heat abnormalities including congenital heart disease, cardiomyoptathies, valvular heart disease, pericardial diseases and rhythm or conduction disorders

  through study completion, an average of 3 years

• incidence of structural heart disease in a population setting

  Structural heart disease refers to any of the following heat abnormalities including congenital heart disease, cardiomyoptathies, valvular heart disease, pericardial diseases and rhythm or conduction disorders

  5 years follow-up

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

2400 individuals, stratifies by place of residence (rural and urban), by age and by sex, in a Spanish community: Salamanca

You may qualify if:

• Any individual willing to participate

You may not qualify if:

• Death people not identified in the community records
• Not able to attend the visit

Sponsors & Collaborators

• AORTICA Group: lead
• University of Salamanca: collaborator

Study Sites (1)

Hospital Universitario de Salamanca

Salamanca, 37002, Spain

Location

Related Publications (1)

• Melero-Alegria JI, Cascon M, Romero A, Vara PP, Barreiro-Perez M, Vicente-Palacios V, Perez-Escanilla F, Hernandez-Hernandez J, Garde B, Cascon S, Martin-Garcia A, Diaz-Pelaez E, de Dios JM, Uribarri A, Jimenez-Candil J, Cruz-Gonzalez I, Blazquez B, Hernandez JM, Sanchez-Pablo C, Santolino I, Ledesma MC, Muriel P, Dorado-Diaz PI, Sanchez PL. SALMANTICOR study. Rationale and design of a population-based study to identify structural heart disease abnormalities: a spatial and machine learning analysis. BMJ Open. 2019 Feb 13;9(2):e024605. doi: 10.1136/bmjopen-2018-024605.

  PMID: 30765403 RESULT

Biospecimen

Retention: SAMPLES WITH DNA

Biomarkers and DNA samples will be stored in a biobank

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: PROSPECTIVE
• Target Duration: 5 Years
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head of Cardiology, PhD, MD

Study Record Dates

• First Submitted: January 10, 2018
• First Posted: February 12, 2018
• Study Start: October 15, 2015
• Primary Completion: May 25, 2018
• Study Completion: May 1, 2019
• Last Updated: June 10, 2019

Record last verified: 2019-06

Data Sharing

• IPD Sharing: Will share

Locations

ES (1)