NCT03419377

Brief Summary

A randomised controlled trial of Lichen Sclerosus in a period of six months measuring Quality of Life and sexuality among women with Lichen Sclerosus.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
158

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2018

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 4, 2018

Completed
22 days until next milestone

First Submitted

Initial submission to the registry

January 26, 2018

Completed
6 days until next milestone

First Posted

Study publicly available on registry

February 1, 2018

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 22, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 22, 2020

Completed
Last Updated

May 27, 2020

Status Verified

May 1, 2020

Enrollment Period

2.4 years

First QC Date

January 26, 2018

Last Update Submit

May 22, 2020

Conditions

Keywords

TreatmentQuality of LifeSexologyWomen

Outcome Measures

Primary Outcomes (1)

  • Quality of Life in women with Lichen Sclerosus

    Change in EuroQol five dimension (EQ-5D) score. The descriptive system comprises 5 dimensions (mobili-ty, self care, usual activities, pain/discomfort, anxiety/depression). However, each dimension has 5 levels: no problems, slight problems, moderate problems, severe problems, and extreme problems. The answers given to EQ-5D permit to find 243 unique health states or can be converted into EQ-5D index an utility scores anchored at 0 for death and 1 for perfect health.

    Six months

Study Arms (2)

Standard care and sexological counseling

EXPERIMENTAL

Standard care including gynecological examination and 6-8 sexological consultations.

Other: Standard care and sexological counseling

Standard care

NO INTERVENTION

Standard care including gynecological examination.

Interventions

6-8 sexological consultants in a period of six months

Standard care and sexological counseling

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients diagnosed with Lichen Sclerosus
  • Age over 18 years

You may not qualify if:

  • Patients who does not understand or speak Danish
  • Patients with a psychiatric diagnosis and can not follow the course

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Vendsyssel Hospital

Hjørring, 9800, Denmark

Location

Related Publications (1)

  • Vittrup G, Westmark S, Riis J, Morup L, Heilesen T, Jensen D, Melgaard D. The Impact of Psychosexual Counseling in Women With Lichen Sclerosus: A Randomized Controlled Trial. J Low Genit Tract Dis. 2022 Jul 1;26(3):258-264. doi: 10.1097/LGT.0000000000000669. Epub 2022 Mar 25.

MeSH Terms

Conditions

Lichen Sclerosus et Atrophicus

Interventions

Standard of Care

Condition Hierarchy (Ancestors)

Lichenoid EruptionsSkin Diseases, PapulosquamousSkin DiseasesSkin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Quality Indicators, Health CareQuality of Health CareHealth Services AdministrationHealth Care Quality, Access, and Evaluation

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Randomized controlled trial
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Coordinator

Study Record Dates

First Submitted

January 26, 2018

First Posted

February 1, 2018

Study Start

January 4, 2018

Primary Completion

May 22, 2020

Study Completion

May 22, 2020

Last Updated

May 27, 2020

Record last verified: 2020-05

Locations