NCT03417674

Brief Summary

Background: Overweight and obesity affect health, quality of life and ability to work. Therefore, the scientifically evaluated program "SHAPE AND MOTION - medically ◦ accompanied ◦ slimming" was developed to support overweight and obese people in weight loss. Method: In a randomized controlled clinical trial, the effect of a lifestyle intervention with meal replacement by formula diet, exercise stimulation, and telemedicine coaching is examined compared to a control group with routine care. The learning contents are taught in 7 group trainings, a practical unit with shopping and cooking training, as well as in 4 individual telephone conversations. The state of health is examined at the beginning, after 12 and 26 weeks. Objective: The aim is to develop a training and counseling program for overweight or obese individuals with diabetes risk or type 2 diabetes, which can be used both for primary and for tertiary prevention of overweight-related diseases.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2018

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 9, 2018

Completed
22 days until next milestone

First Posted

Study publicly available on registry

January 31, 2018

Completed
10 days until next milestone

Study Start

First participant enrolled

February 10, 2018

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 10, 2019

Completed
1.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2020

Completed
Last Updated

October 12, 2021

Status Verified

October 1, 2021

Enrollment Period

1.2 years

First QC Date

January 9, 2018

Last Update Submit

October 11, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Weight loss in kg

    Estimated treatment difference

    26 weeks

Secondary Outcomes (23)

  • body mass index in kg/m2

    26 weeks

  • waist circumference in cm

    26 weeks

  • hip circumference in cm

    26 weeks

  • fat mass in kg

    26 weeks

  • lean body mass in kg

    26 weeks

  • +18 more secondary outcomes

Study Arms (2)

Intervention group

EXPERIMENTAL

Lifestyle intervention with meal replacement by formula diet, exercise stimulation, and telemedicine coaching.

Combination Product: Lifestyle intervention

Control group

NO INTERVENTION

Routine care.

Interventions

Lifestyle interventionCOMBINATION_PRODUCT

Meal replacement by formula diet, exercise stimulation, and telemedicine coaching.

Intervention group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Body mass index ≥ 25 kg/m2

You may not qualify if:

  • acute diseases such as respiratory or gastrointestinal infections
  • severe diseases such as tumors, chronic obstructive pulmonary disease (COPD), asthma, dementia, chronic bowel disease, psychosis, liver cirrhosis, (macro) nephropathy, renal insufficiency with glomerular filtration rate (GFR) \<30
  • ongoing chemotherapy, chron. Cortisone treatment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

West-German Centre of Diabetes and Health

Düsseldorf, 40591, Germany

Location

MeSH Terms

Conditions

OverweightObesity

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Stephan Martin, MD

    West-German Centre of Diabetes and Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
SEQUENTIAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 9, 2018

First Posted

January 31, 2018

Study Start

February 10, 2018

Primary Completion

April 10, 2019

Study Completion

December 31, 2020

Last Updated

October 12, 2021

Record last verified: 2021-10

Data Sharing

IPD Sharing
Will not share

Locations