NCT03416907

Brief Summary

This study will test whether different formats of medical informed consent documents can help improve understanding and confidence in decision-making for clinical trials. The study will be primarily run through an online survey.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 27, 2017

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2017

Completed
8 days until next milestone

First Submitted

Initial submission to the registry

January 8, 2018

Completed
23 days until next milestone

First Posted

Study publicly available on registry

January 31, 2018

Completed
Last Updated

January 31, 2018

Status Verified

January 1, 2018

Enrollment Period

1 month

First QC Date

January 8, 2018

Last Update Submit

January 24, 2018

Conditions

Keywords

Informed consent

Outcome Measures

Primary Outcomes (1)

  • Score for high impact questions

    Sum of correct answers (T/F) for any item relating to material that was rated as 50 or higher on impact on willingness to enroll in a previous study.

    through study completion, an average of 30 minutes

Secondary Outcomes (11)

  • Score for low impact questions

    through study completion, an average of 30 minutes

  • Total score for all questions

    through study completion, an average of 30 minutes

  • Interaction effect of format and importance on likelihood of correct answer

    through study completion, an average of 30 minutes

  • Scores for different information categories

    through study completion, an average of 30 minutes

  • Effect of location on score

    through study completion, an average of 30 minutes

  • +6 more secondary outcomes

Other Outcomes (1)

  • Participant's free-response text describing what was learned from reading the informed consent document

    through study completion, an average of 30 minutes

Study Arms (5)

Original

ACTIVE COMPARATOR

Participants will review the full-length, original consent form for the clinical trial.

Behavioral: Original consent form

Shortened

EXPERIMENTAL

Participants will review a shortened consent form for the clinical trial, which includes only material indicated as important by 2/3 of participants from a previous study.

Behavioral: Shortened consent form

Reordered

EXPERIMENTAL

Participants will review a reordered, shortened consent form. This form is based on the shortened consent form, but the sections are reordered based on a previous study, such that sentences previously rated as more likely to impact a participant's decision is more likely to be presented first (except for an initial introductory section).

Behavioral: Reordered, shortened consent form

Highlighted

EXPERIMENTAL

Participants will review a shortened consent form with a highlights box, where the highlights box includes the 10 sentences rates as most likely to impact a participant's decision from a previous study.

Behavioral: Shortened consent form with a highlights box

Interactive

EXPERIMENTAL

Participants will review an interactive, shortened consent form, where hyperlinks to different sections of the consent form are provided. The landing page includes the introductory section.

Behavioral: Interactive, shortened consent form

Interventions

Participants will review the full-length, original consent form for the clinical trial.

Original

Participants will review a shortened consent form for the clinical trial, which includes only material indicated as important by 2/3 of participants from a previous study.

Shortened

Participants will review a reordered, shortened consent form. This form is based on the shortened consent form, but the sections are reordered based on a previous study, such that sentences previously rated as more likely to impact a participant's decision is more likely to be presented first (except for an initial introductory section).

Reordered

Participants will review a shortened consent form with a highlights box, where the highlights box includes the 10 sentences rates as most likely to impact a participant's decision from a previous study.

Highlighted

Participants will review an interactive, shortened consent form, where hyperlinks to different sections of the consent form are provided. The landing page includes the introductory section.

Interactive

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Years Old or Older
  • Read and agreed to informed consent
  • Indicated desire to participate
  • Diagnosed with asthma
  • US resident

You may not qualify if:

  • Participants from whom we receive multiple responses will be dropped from analysis (but will be compensated for participation)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Carnegie Mellon University

Pittsburgh, Pennsylvania, 15213, United States

Location

MeSH Terms

Conditions

Asthma

Interventions

Drug Interactions

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Intervention Hierarchy (Ancestors)

Pharmacological PhenomenaPharmacological and Toxicological PhenomenaPhysiological Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 8, 2018

First Posted

January 31, 2018

Study Start

November 27, 2017

Primary Completion

December 31, 2017

Study Completion

December 31, 2017

Last Updated

January 31, 2018

Record last verified: 2018-01

Locations