Effect of Implementation Of Outreach Behavioral Change Program for HCV Elimination

NCT03415334 | Completed DMC

• 1 other identifier: 66187
• Study Type: interventional
• Target: 3,575
• Locations: 0 countries
• Sites: N/A

Brief Summary

Elimination of hepatitis C virus (HCV) is the process of stopping sustained transmission of viral hepatitis, reducing its incidence to zero and providing access to safe, affordable and effective treatment and care for everyone. Consequently, HCV will not be a leading cause of mortality (1). The World Health Organization (WHO) called for comprehensive programs that enhance access to affordable treatment in developing countries as HCV was considered a global public health priority since 2010 and set criteria of elimination(2). A disease is eliminated if its controlling efforts are sufficient to prevent an epidemic from occurring in a given geographical area and measures must be continued to prevent re-establishment of transmission (3) According to the Centers for Disease Control and Prevention (CDC), HCV now surpasses HIV as the nation's deadliest blood-borne disease. In addition, the majority of infected persons are not aware of their infection as they are not clinically ill and there is no vaccine for Hepatitis C. It is well known that the best way to prevent Hepatitis C is by avoiding behaviors that can spread the disease. (4) This study is a way forward for the elimination of hepatitis C from Egypt through applying different public health approaches for motivating people and changing villagers' risky behaviors aiming at increasing the number of people adopting healthy practices for decreasing the incidence rate of hepatitis in El Othmaneya village. The proposed activities along one year were applied for 3575 inhabitants aged more than 12 years who were get tested for Hepatitis C Virus (HCV) antibodies. The initiative activities were provided by community-led coalition and supported technically by the Egyptian Liver Research Institute and Hospital (ELRIAH).

Conditions

Hepatitis C and B VIRUS Screening, Awareness and Behavior Assessment and Evaluation for All Inhabitants Above Twelve Years of Al Othmaneya Village

Keywords

Hepatitis C; social marketing; Communication for behavior development

Outcome Measures

Primary Outcomes (4)

• percent change of awareness using pre and post intervention questionnaire for participants who became aware of the problem

  1. Using previously used syringes 2. Sharing shaving equipment, nail cutters or through needle stick injury 3. Defect in infection control process during sessions for teeth treatment 4. sharing tooth brush with other family members 5. It is better for HCV patients to get vaccinated with Hepatitis B vaccines 6. Using new syringes/sharp instruments which are not used before could reduce the risk of becoming infected with HCV 7. Awareness by the recommended behaviors can limit the complication and propagation of HCV infection

  two years

• Percent change using pre and post intervention questionnaire for participants who became concerned about the problem,acquired knowledge and internalized the knowledge

  Perception: 1. HCV is a serious disease 2. HCC is a complication of HCV 3. Cirrhosis is a complication of HCV 4. Early diagnosis could make a change in patients' health 5. Fatigue from least effort is symptom of HCV

  two years

• Percent change using pre and post intervention questionnaire for participants who became motivated and had positive attitude to do something about the problem

  The Attitude: 1. Asking the barber: to change the shaving tools in front of them 2. to use their own shaving machine 3. Checking for sterilized tools at dentist clinic 4. Telling the dentist if they have/ had HCV

  two years

• Percent change of behavior using pre and post intervention questionnaire for participants who tried out /rejected or adopted the recommended behavior

  The tried out / rejected or adopted : Not sharing: 1. nail cutters and scissors between family members 2. loofah and sponge for personal cleaning 3. the use of scarves' pins by the veiled females in the same family 4. other's shaving tools 5. others tooth brushes

  two tears

Study Arms (1)

behavioral change

OTHER

two approaches for behavior changes : social marketing and behavioral development

Behavioral: behavioral development for change

Interventions

behavioral development for change BEHAVIORAL

1. Social Marketing Principles (4 Ps) Product, price, place and promotion 2. Communication for Behavior Development Approach 1. Interpersonal communication campaigns (IPC) 2. Mass media and public gathering awareness campaigns 3. Public health awareness campaigns 4. A village hotline and local satellite channel 5. School awareness raising events

Also known as: 2 approaches were used : 1) Social Marketing Principles (4Ps) 2) Communication for Behavior Development Approach

behavioral change

Eligibility Criteria

• Age: 12 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• All village inhabitants starting from 12 years old

You may not qualify if:

• inhabitants less than 12 years old

Sponsors & Collaborators

• National Research Centre, Egypt: lead
• Egyptian Liver Hospital: collaborator

Related Publications (4)

• Barrett S. Eradication versus control: the economics of global infectious disease policies. Bull World Health Organ. 2004 Sep;82(9):683-8.

  PMID: 15628206 BACKGROUND

• 4) Center for Disease Control (CDC). Division of Viral Hepatitis (DVH) Strategic Plan, 2016-2020: Bringing Together Science and Public-Health Practices for the Elimination of Viral Hepatitis. (2016). http://www.cdc.gov/hepatitis/pdfs/dvh-strategicplan2016-2020-draft.

  BACKGROUND

• WORLD HEPATITIS SUMMIT HARNESSES GLOBAL MOMENTUM TO ELIMINATE VIRAL HEPATITIS. Cent Eur J Public Health. 2015 Sep;23(3):272. No abstract available.

  PMID: 26618210 BACKGROUND

• Heymann DL. Control, elimination, eradication and re-emergence of infectious diseases: getting the message right. Bull World Health Organ. 2006 Feb;84(2):82. doi: 10.2471/blt.05.029512. Epub 2006 Feb 23. No abstract available.

  PMID: 16501719 BACKGROUND

Related Links

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MeSH Terms

Conditions

Hepatitis C

Condition Hierarchy (Ancestors)

Blood-Borne Infections; Communicable Diseases; Infections; Hepatitis, Viral, Human; Virus Diseases; Flaviviridae Infections; RNA Virus Infections; Hepatitis; Liver Diseases; Digestive System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Masking Details: care providers were not the same persons who did the assessment and the evaluation .
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head of community medicine research department

Model Details: The study passed through three phases; first phase pre-interventional assessment of level of the recommended behavior development towards eradication of HCV, dominance of current risky behaviors and the wrong believes regarding HCV . The second phase included: community based interventions and the setting of the educational activation plan for HCV elimination in the village and the third was post-intervention evaluation of the change of level of community behaviors adoption according to a preset indicators.

Study Record Dates

• First Submitted: January 13, 2018
• First Posted: January 30, 2018
• Study Start: May 21, 2015
• Primary Completion: May 13, 2017
• Study Completion: October 21, 2017
• Last Updated: January 30, 2018

Record last verified: 2018-01