Comparative Effectiveness Study of Transthoracic and Transesophageal Echocardiography in Stroke

NCT03411642 | Completed Results

• 1 other identifier: PV5225
• Study Type: observational
• Target: 494
• Locations: 1 country
• Sites: 4

Brief Summary

The Comparative Effectiveness Study of Transthoracic and Transesophageal Echocardiography in Stroke (CONTEST) aims at assessing the diagnostic value of transesophageal echocardiography (TEE) and transthoracic echocardiography (TTE) with regards to treatment consequences in patients with acute ischemic stroke.

Conditions

Stroke, Acute

Keywords

Stroke, echocardiography

Outcome Measures

Primary Outcomes (1)

• Number of Participants With Diagnostic Findings That Lead to a Change in Acute Treatment or Treatment for Secondary Prevention

  Treatment relevant diagnostic findings identified by a central endpoint adjudication committee comprising both cardiologists and neurologists.

  Inpatient treatment on a stroke unit usually <7 days

Secondary Outcomes (1)

• Number of Patients With Change of Assessment of Stroke Etiology After TEE

  Inpatient treatment on a stroke unit usually <7 days

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with acute stroke in whom echocardiography is indicated will be studied by TTE and TEE.

You may qualify if:

• acute ischemic stroke or transitory ischemic attack (TIA)
• age ≥18 years
• informed consent

You may not qualify if:

• Patients with already defined stroke etiology and determined secondary prevention treatment strategy prior to echocardiography (e.g. atrial fibrillation, carotid artery stenosis, cervical artery dissection)

Sponsors & Collaborators

• Universitätsklinikum Hamburg-Eppendorf: lead
• Albertinen Krankenhaus: collaborator
• Regio Kliniken: collaborator
• Helios University Hospital Wuppertal: collaborator
• Kreiskliniken Reutlingen: collaborator
• Klinikum Karlsbad-Langensteinbach: collaborator

Study Sites (4)

Universitätsklinikum Hamburg-Eppendorf

Hamburg, 20246, Germany

Location

Albertinen-Krankenhaus

Hamburg, 22457, Germany

Location

Regio Klinikum Pinneberg

Pinneberg, 25421, Germany

Location

Kreiskliniken Reutlingen

Reutlingen, 72764, Germany

Location

Related Publications (1)

• Thomalla G, Upneja M, Camen S, Jensen M, Schroder J, Barow E, Boskamp S, Ostermeier B, Kissling S, Leinisch E, Tiburtius C, Clausen H, Cheng B, Blankenberg S, Nedelmann M, Steinbrecher A, Andres F, Rosenkranz M, Sinning C, Schnabel RB, Gerloff C. Treatment-Relevant Findings in Transesophageal Echocardiography After Stroke: A Prospective Multicenter Cohort Study. Stroke. 2022 Jan;53(1):177-184. doi: 10.1161/STROKEAHA.121.034868. Epub 2021 Sep 9.

  PMID: 34496617 DERIVED

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Results Point of Contact

• Title: Prof. Dr. Götz Thomalla
• Organization: University Medical Center Hamburg-Eppendorf

thomalla@uke.de

+4940501377410

Study Officials

• Götz Thomalla, MD

  Universitätsklinikum Hamburg-Eppendorf

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 19, 2018
• First Posted: January 26, 2018
• Study Start: July 1, 2017
• Primary Completion: June 30, 2019
• Study Completion: August 31, 2019
• Last Updated: September 13, 2023
• Results First Posted: September 13, 2023

Record last verified: 2022-11

Locations

DE (4)