NCT03410563

Brief Summary

The study investigates the analgesic effect of different auditory inputs. Employing a within-subject design, the study includes healthy participants that are exposed to thermal stimuli while listening to three different auditory inputs. By repeating this on separate test days, the involvement of bodily processes is investigated.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2018

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 3, 2018

Completed
15 days until next milestone

First Submitted

Initial submission to the registry

January 18, 2018

Completed
7 days until next milestone

First Posted

Study publicly available on registry

January 25, 2018

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2018

Completed
Last Updated

October 11, 2018

Status Verified

January 1, 2018

Enrollment Period

4 months

First QC Date

January 18, 2018

Last Update Submit

October 10, 2018

Conditions

Analgesia

Keywords

PainAuditory inputs

Outcome Measures

Primary Outcomes (1)

  • Visual analogue scales

    Acute pain assessed on visual analogue scales (0-100) examining pain intensity and pain unpleasantness

    An average of 3 weeks (Participants are tested at three different test days across an average of 3 weeks; the primary outcome measure will be assessed after each thermal stimulus at the three test days)

Study Arms (1)

Healthy participants

Behavioral: Auditory inputs

Interventions

Auditory inputsBEHAVIORAL

Three different auditory inputs

Healthy participants

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

Healthy participants

You may qualify if:

  • Healthy participants with normal hearing

You may not qualify if:

  • Chronic pain conditions
  • Other medical, psychiatric or neurological disorders
  • Use of pain-relieving medication 24 hours prior to testing

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Psychology and Behavioural Sciences

Aarhus C, 8000, Denmark

Location

Related Publications (1)

  • Lunde SJ, Vuust P, Garza-Villarreal EA, Kirsch I, Moller A, Vase L. Music-Induced Analgesia in Healthy Participants Is Associated With Expected Pain Levels but Not Opioid or Dopamine-Dependent Mechanisms. Front Pain Res (Lausanne). 2022 Apr 4;3:734999. doi: 10.3389/fpain.2022.734999. eCollection 2022.

    PMID: 35445208DERIVED

MeSH Terms

Conditions

AgnosiaPain

Condition Hierarchy (Ancestors)

Perceptual DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 18, 2018

First Posted

January 25, 2018

Study Start

January 3, 2018

Primary Completion

May 1, 2018

Study Completion

May 1, 2018

Last Updated

October 11, 2018

Record last verified: 2018-01

Data Sharing

IPD Sharing
Will not share

Locations

DK(1)