NCT03406637

Brief Summary

Patients who received a total knee endoprosthesis BPK-S Integration between 2011 and 2013 will be invited to participate in this PMCF study provided sufficient source data documentation is available regarding preoperative, intraoperative and early postoperative follow-up assessments. Only patients providing written informed consent prior to any study data collection can take part in the study. Preoperative, intraoperative and early postoperative data (3 months, 1 year and 2 years after implantation) will be collected retrospectively. Additional long-term follow-up of one visit (year 7 after implantation) will be documented prospectively. Only parameters assessed in clinical standard care for follow-up (implant control) visits will be collected for this PMCF study. Radiological assessment of the implanted prosthesis will only be conducted if medically indicated according to the investigator. No additional study related assessment will be performed. Only anonymized data will be used in this observational study to protect patient privacy. No personally identifiable information will be collected.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
62

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Oct 2018

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 8, 2018

Completed
15 days until next milestone

First Posted

Study publicly available on registry

January 23, 2018

Completed
9 months until next milestone

Study Start

First participant enrolled

October 17, 2018

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 2, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 2, 2020

Completed
Last Updated

March 6, 2020

Status Verified

March 1, 2020

Enrollment Period

1.4 years

First QC Date

January 8, 2018

Last Update Submit

March 5, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Patient relevant benefit after 5 years

    improvement of KSS-Score by at least one category as compared to preoperative basic assessment

    7 years

Secondary Outcomes (8)

  • Safety parameters

    7 years

  • Patient relevant benefit as measured by American Knee Society Score

    1 year

  • Implant Loosening Number

    7 years

  • Implant Loosening Reason

    7 years

  • Revision Number

    7 years

  • +3 more secondary outcomes

Interventions

primary total knee endoprosthesis

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients that received a BPK-S Integration in the variant CoCr as primary total knee endoprosthesis between 2011 and 2013 implanted by the investigator

You may qualify if:

  • Patients that received a total primary knee endoprosthesis BPK-S Integration (Co28Cr6Mo) between 2011 and 2013
  • Patients that agree to participate and give written informed consent to the anonymized retrospective and prospective data collection within the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Centre Hospitalier de Wallonie picarde - CHwapi A.S.B.L

Tournai, 7500, Belgium

Location

Medical Center Tournai

Tournai, 7500, Belgium

Location

MeSH Terms

Conditions

Osteoarthritis, KneeJoint Instability

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
OTHER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 8, 2018

First Posted

January 23, 2018

Study Start

October 17, 2018

Primary Completion

March 2, 2020

Study Completion

March 2, 2020

Last Updated

March 6, 2020

Record last verified: 2020-03

Locations