Outcome of Arterio-venous Fistula for Adult Hemodialysis Patients in Assiut Governorate

NCT03397381 | Unknown DMC

• 1 other identifier: 17200155
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

identification of the factors that affect the outcome of arteriovenous fistula in chronic renal failure patients that newly established regular dialysis in Assiut Governorate

1. 1.To study the factors that influence the outcome of AVF
2. 2.To evaluate the vascular complications of AVF as occlusion, rupture, aneurysmal dilation and hand ischemia

Conditions

Chronic Renal Failure

Outcome Measures

Primary Outcomes (1)

• the number of new renal failure patients with failed arteriovenous fistula as measured with arteriovenous duplex ultrasound imaging peak systolic velocity and end-diastolic velocity in Assiut Governorate

  the arteriovenous fistula will be named fail if one or more of the following 1. No Doppler signal 2. Ratio of peak systolic velocity at stenosis to peak systolic velocity at 2 cm beyond anastomosis (if normal)appearing \>3 3. Intraluminal echogenicity 4. Graft walls appear collapsed

  3 years

Secondary Outcomes (1)

• the number deaths of renal failure patients on regular dialysis related to AVF complications in Assiut Governorate

  3 years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Chronic renal Failure on regular dialysis

You may qualify if:

• all adult hemodialysis Patients in Assiut Government are eligible for enrollment if they are newly dialyzed via AVF and agree to participate in the study

You may not qualify if:

• Patients are not dialyzed with AVF

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Hanan

Asyut, 71515, Egypt

RECRUITING

Related Publications (5)

• Stolic R. Most important chronic complications of arteriovenous fistulas for hemodialysis. Med Princ Pract. 2013;22(3):220-8. doi: 10.1159/000343669. Epub 2012 Nov 2.

  PMID: 23128647 RESULT

• Lok CE. Fistula first initiative: advantages and pitfalls. Clin J Am Soc Nephrol. 2007 Sep;2(5):1043-53. doi: 10.2215/CJN.01080307. Epub 2007 Aug 16. No abstract available.

  PMID: 17702726 RESULT

• Valliant A, McComb K. Vascular Access Monitoring and Surveillance: An Update. Adv Chronic Kidney Dis. 2015 Nov;22(6):446-52. doi: 10.1053/j.ackd.2015.06.002.

  PMID: 26524949 RESULT

• Hammes M. Hemodynamic and biologic determinates of arteriovenous fistula outcomes in renal failure patients. Biomed Res Int. 2015;2015:171674. doi: 10.1155/2015/171674. Epub 2015 Oct 1.

  PMID: 26495286 RESULT

• Padberg FT Jr, Calligaro KD, Sidawy AN. Complications of arteriovenous hemodialysis access: recognition and management. J Vasc Surg. 2008 Nov;48(5 Suppl):55S-80S. doi: 10.1016/j.jvs.2008.08.067.

  PMID: 19000594 RESULT

MeSH Terms

Conditions

Kidney Failure, Chronic

Condition Hierarchy (Ancestors)

Renal Insufficiency, Chronic; Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Hanan S Mahrous, MD

  Assiut University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Hanan S Mahrous, MD

CONTACT

0201017031500; mostafak198173@yahoo.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: director of Renal dialysis Unit of Assiut Health directorate

Study Record Dates

• First Submitted: December 26, 2017
• First Posted: January 12, 2018
• Study Start: January 20, 2018
• Primary Completion: January 1, 2021
• Study Completion: January 1, 2022
• Last Updated: January 11, 2019

Record last verified: 2019-01

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)