NCT03391063

Brief Summary

the trial is done in order to reinforce polyamide to improve its modulus of elasticity to be able to use it as a denture base material in all clinical cases

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
38

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2018

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 29, 2017

Completed
7 days until next milestone

First Posted

Study publicly available on registry

January 5, 2018

Completed
27 days until next milestone

Study Start

First participant enrolled

February 1, 2018

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2018

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2018

Completed
Last Updated

January 5, 2018

Status Verified

January 1, 2018

Enrollment Period

3 months

First QC Date

December 29, 2017

Last Update Submit

January 4, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • chewing efficiency assessed using sieving method

    chewing efficiency of the mandibular complete denture

    6 weeks

Study Arms (2)

reinforced polyamide denture base

EXPERIMENTAL

metal reinforced polyamide denture base

Other: polyamide

conventional acrylic resin denture base

ACTIVE COMPARATOR

conventional heat cured acrylic resin denture base

Other: heat cured acrylic resin

Interventions

metal reinforced polyamide denture base material

Also known as: nylon
reinforced polyamide denture base

conventional heat cured acrylic resin denture base material

conventional acrylic resin denture base

Eligibility Criteria

Age55 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Male or female patient with age range (45-55) completely edentulous and in good medical condition.
  • All patients have skeletal Angle's class I maxillo-mandibular relationship and have sufficient interarch distance.
  • Free from any systemic or neuromuscular disorder that might affect chewing efficiency of masticatory muscles.
  • Free from any tempro-mandibular joint disorder.
  • The patients have good oral hygiene.
  • The edentulous ridges should be covered by firm healthy mucosa.
  • Healthy and co-operative patients.

You may not qualify if:

  • Patients with bad habits as severe clenching or bruxism, drug or alcohol addiction, moderate or heavy smoking (greater than 10 cigarettes per day).
  • Previous history of radiotherapy or chemotherapy.
  • Any skeletal problem dictates surgical intervention.
  • Patients having hormonal disorders as diabetes, thyroid or parathyroid hormonal diseases were not included.
  • Patient with xerostomia or excessive salivation.
  • No intraoral soft and hard tissue pathosis.
  • Psychiatric problems.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Vojdani M, Giti R. Polyamide as a Denture Base Material: A Literature Review. J Dent (Shiraz). 2015 Mar;16(1 Suppl):1-9.

    PMID: 26106628BACKGROUND

MeSH Terms

Conditions

Mouth, Edentulous

Interventions

Nylons

Condition Hierarchy (Ancestors)

Mouth DiseasesStomatognathic DiseasesTooth Diseases

Intervention Hierarchy (Ancestors)

PlasticsPolymersMacromolecular SubstancesBiomedical and Dental MaterialsManufactured MaterialsTechnology, Industry, and Agriculture

Central Study Contacts

mahmoud abdallah abdelomttaleb, B.D.S

CONTACT

Amal Kaddah

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
dentist

Study Record Dates

First Submitted

December 29, 2017

First Posted

January 5, 2018

Study Start

February 1, 2018

Primary Completion

May 1, 2018

Study Completion

July 1, 2018

Last Updated

January 5, 2018

Record last verified: 2018-01