NCT03377894

Brief Summary

comparison between blunt versus sharp expansion of uterine incision at lower segment cesarean section in primigravida as regards the intra-operative blood loss \& postoperative pain

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for phase_2

Timeline
Completed

Started Dec 2017

Shorter than P25 for phase_2

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2017

Completed
9 days until next milestone

First Submitted

Initial submission to the registry

December 10, 2017

Completed
9 days until next milestone

First Posted

Study publicly available on registry

December 19, 2017

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2018

Completed
Last Updated

December 19, 2017

Status Verified

December 1, 2017

Enrollment Period

3 months

First QC Date

December 10, 2017

Last Update Submit

December 13, 2017

Conditions

Outcome Measures

Primary Outcomes (3)

  • post operative pain

    Post-operative pain is analyzed by using 4 point verbal rating scale (VRS) which consists of a list of adjectives describing different levels of pain intensity i.e (no pain =1, mild pain = 2, moderate pain = 3, severe pain = 4)

    one hour after cs

  • intraoperative bleeding

    The intra-operative blood loss is evaluated by towels as follows: The surgical towels will be weighed (gm) before and after the operation, and the difference in weight between dry and soaked towels will be calculated. Blood loss during the operation will be calculated by adding the volume of the contents of the suction bottle (ml) to the difference in weight of towels (gm) (weight of soaked towels - weight of dry towels).

    from skin incision till skin closure

  • The operative time is recorded in minutes

    The operative time is recorded in minutes

    from skin incision till skin closure

Study Arms (2)

• Group (A) blunt incision

ACTIVE COMPARATOR

100 primigravidas at term who underwent elective transverse lower segment Cesarean section for the first time among the age group of 20 - 37 years with a singleton pregnancy. undergoing blunt uterine incision expansion

Procedure: blunt uterine incision expansion

• Group (B) sharp incision

ACTIVE COMPARATOR

100 primigravidas, at term who underwent elective transverse lower segment Cesarean section for the first time among the age group of 20 - 37 years with a singleton pregnancy undergoing sharp uterine incision expansion

Procedure: sharp uterine incision expansion

Interventions

blunt uterine incision expansion

• Group (A) blunt incision

sharp uterine incision expansion

• Group (B) sharp incision

Eligibility Criteria

Age20 Years - 37 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • singleton pregnancy.

You may not qualify if:

  • previous PID
  • any medical or psychiatric
  • patients with BMI ≥ 40
  • multigravidas
  • chronic analgesia use,
  • allergy to analgesics,
  • multiple pregnancies are also excluded

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kasr El Ainiy Hospital

Cairo, 11562, Egypt

Location

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
lecturer of obstetrics and gynecology

Study Record Dates

First Submitted

December 10, 2017

First Posted

December 19, 2017

Study Start

December 1, 2017

Primary Completion

March 1, 2018

Study Completion

March 1, 2018

Last Updated

December 19, 2017

Record last verified: 2017-12

Locations