NCT03376399

Brief Summary

The purpose of this registry is to evaluate if sleeve gastrectomy surgery will help with symptoms of delayed gastric emptying for patients suffering from diabetic gastroparesis.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Oct 2017

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 25, 2017

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

December 13, 2017

Completed
5 days until next milestone

First Posted

Study publicly available on registry

December 18, 2017

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2020

Completed
Last Updated

July 2, 2020

Status Verified

June 1, 2020

Enrollment Period

3.2 years

First QC Date

December 13, 2017

Last Update Submit

June 30, 2020

Conditions

Keywords

Sleeve GastrectomyGastric EmptyingDiabetic GastroparesisBariatric Surgery Candidate

Outcome Measures

Primary Outcomes (1)

  • Examine gastroparesis symptoms

    Administer the Gastroparesis Cardinal Symptom Index (GCSI). The GCSI consists of three subscales: (1) Nausea/vomiting, (2) Fullness/early satiety, and (3) Bloating/distention. The average score is calculated from these three subscales with higher scores indicating greater symptom severity. The symptoms are rated on a scale from 0-5 with zero reflecting no symptoms and 5 indicating very severe symptoms.

    1 year

Interventions

Patients with an established diagnosis of Diabetic Gastroparesis that are interested in a sleeve gastrectomy for weight loss will be asked to participate in the registry. Once the consent process is complete the patient will be asked to complete the Gastroparesis Cardinal Symptom Index Questionnaire prior to weight loss surgery and 30 days, 3 months, 6 months and 12 months after surgery.

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study group will be patients with diabetic gastroparesis who qualify for bariatric weight loss surgery (BMI \>35, insurance/medicare bariatric coverage). These patients are referred by gastroenterologists and/or endocrinologists with established diagnosis of diabetic gastroparesis confirmed via delayed gastric emptying on scintigraphy. All available treatment options will be discussed with every qualifying patient. Patients opting for sleeve gastrectomy will be invited to participate in the registry.

You may qualify if:

  • Age 18 years and above
  • BMI \> 35
  • Diagnosis of diabetic gastroparesis as confirmed via scintigraphy
  • Subject opting to undergo sleeve gastrectomy

You may not qualify if:

  • \- Any previous weight loss surgery or prior gastrectomies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Baylor Weight Loss Surgery Center

Dallas, Texas, 75231, United States

Location

MeSH Terms

Conditions

Weight Loss

Condition Hierarchy (Ancestors)

Body Weight ChangesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Daniel Davis, DO

    Baylor Scott & White, Baylor University Medical Center

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 13, 2017

First Posted

December 18, 2017

Study Start

October 25, 2017

Primary Completion

December 31, 2020

Study Completion

December 31, 2020

Last Updated

July 2, 2020

Record last verified: 2020-06

Locations