Prevalence of Oral Manifestations of Iron Deficiency Anemia in a Sample of Egyptian Population

NCT03365570 | Completed

• 1 other identifier: oral lesions and anemia
• Study Type: observational
• Target: 180
• Locations: 1 country
• Sites: 1

Brief Summary

According to WHO Reportin 2002, iron deficiency anemia was considered to be the most important contributing factor to the global burden of anemia. Children and women in reproductive ages are more at risk factor for developing iron deficiency anemia.No previous study has been held to assess prevalence of oral manifestations of iron deficiency anemia as a hospital-based cross-sectional study on a sample of Egyptian patients in hematology department (no previous data recorded).

Conditions

Iron Deficiency Anemia

Keywords

hemoglobin, iron, oral lesions, oral manifestations,cross-sectional study

Outcome Measures

Primary Outcomes (1)

• Prevalence of oral mucosal lesions

  Presence of oral mucosal lesions will be assessed by clinical picture into dichotomous outcome (Yes/No) and percentage of each.

  15 minutes

Eligibility Criteria

• Age: Up to 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants: Egyptian patients diagnosed with Iron deficiency anemia that attending the Hematology department at El Qasr Al-Einy Cairo University Hospital will be enrolled in the study. The age of participant enroll will be up to 70 years old, males and females will be included. For each eligible participant, a full history will be obtained according to an assessment sheet, followed by clinical examination which will be done through an interview between the investigator and the patient. All participants will be asked to sign a study-related informed consent.

You may qualify if:

• Patients diagnosed with iron deficiency anemia based on their blood tests.
• Age: by maximum 70 years old.
• Males and females will be included.

You may not qualify if:

• Patients suffering from any other systemic diseases known to influence oral and maxillofacial manifestations will be excluded.
• Patients suffering from any other systemic diseases known to cause IDA as secondary condition will be excluded.
• Patients on drug therapy that may have oral mucosal manifestations.
• Lesions appear because of existing local factors for example traumatic ulcer on the tongue because of sharp tooth against tongue, angular cheilitis because of poor denture design and older age patients.
• Inflammatory diseases, malignancy, or recent surgery were excluded.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo University

Cairo, 12613, Egypt

Location

Related Publications (3)

• DeLoughery TG. Iron Deficiency Anemia. Med Clin North Am. 2017 Mar;101(2):319-332. doi: 10.1016/j.mcna.2016.09.004. Epub 2016 Dec 8.

  PMID: 28189173 BACKGROUND

• Rohani B. Oral manifestations and blood profile in patients with iron deficiency anemia. J Formos Med Assoc. 2015 Jan;114(1):97. doi: 10.1016/j.jfma.2014.07.004. Epub 2014 Aug 10. No abstract available.

  PMID: 25115528 RESULT

• Wu YC, Wang YP, Chang JY, Cheng SJ, Chen HM, Sun A. Oral manifestations and blood profile in patients with iron deficiency anemia. J Formos Med Assoc. 2014 Feb;113(2):83-7. doi: 10.1016/j.jfma.2013.11.010. Epub 2013 Dec 30.

  PMID: 24388269 RESULT

MeSH Terms

Conditions

Anemia, Iron-Deficiency; Oral Manifestations

Condition Hierarchy (Ancestors)

Anemia, Hypochromic; Anemia; Hematologic Diseases; Hemic and Lymphatic Diseases; Iron Deficiencies; Iron Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Mouth Diseases; Stomatognathic Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Fatheya Zahran, Professor

  Head of the Department of Oral Medicine and periodontology Cairo University

  STUDY CHAIR

• Eman Alsheikh

  Master student

  PRINCIPAL INVESTIGATOR

• Eman Mo Amr, A.Professor

  associate professor in the Department of Oral Medicine and periodontology Cairo University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: BDS, Master student at oral medicine department

Study Record Dates

• First Submitted: December 2, 2017
• First Posted: December 7, 2017
• Study Start: May 1, 2018
• Primary Completion: November 1, 2018
• Study Completion: November 9, 2018
• Last Updated: January 30, 2019

Record last verified: 2019-01

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)