NCT03363750

Brief Summary

The Center for Mind -Body Medicine has developed a mind-body skills group program that incorporates meditation, guided imagery, breathing techniques, autogenic training, biofeedback, genograms, and self-expression through words, drawings, and movement. These mind-body skills are designed to increase self-awareness and self-regulation. This program has been shown to significantly improve depression symptoms in children and adolescents with posttraumatic stress disorder in Gaza, but it has not yet been tested in a US adolescent population. The purpose of this study is to determine the feasibility of using mind-body skills groups to reduce depression in adolescents and to investigate the effects of the program on factors such as self-efficacy, mindfulness and rumination which are likely to mediate improvement.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
49

participants targeted

Target at P25-P50 for not_applicable depression

Timeline
Completed

Started Jan 2018

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 21, 2017

Completed
15 days until next milestone

First Posted

Study publicly available on registry

December 6, 2017

Completed
2 months until next milestone

Study Start

First participant enrolled

January 25, 2018

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 4, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 4, 2019

Completed
Last Updated

March 10, 2020

Status Verified

March 1, 2020

Enrollment Period

1.6 years

First QC Date

November 21, 2017

Last Update Submit

March 9, 2020

Conditions

Keywords

DepressionAdolescentmind-body-skillsgroup therapyprimary care

Outcome Measures

Primary Outcomes (2)

  • Change in Children's Depression Inventory-2 (CDI-2) scores

    self report long version (28 items) to assess the presence and severity of depressive symptoms in children

    from baseline to within one month after end of intervention

  • Change in Children's Depression Inventory-2 (CDI-2) scores

    self report long version (28 items) to assess the presence and severity of depressive symptoms in children

    from baseline to approximately 3 months after end of intervention

Secondary Outcomes (18)

  • Change in Patient Health Questionnaire-9 (PHQ-9) score

    from baseline to within one month after end of intervention

  • Change in Patient Health Questionnaire-9 (PHQ-9) score

    from baseline to approximately 3 months after end of intervention

  • Change in Rumination Subscale of the Children's Response Style Questionnaire Score

    from baseline to within one month after end of intervention

  • Change in Rumination Subscale of the Children's Response Style Questionnaire Score

    from baseline to approximately 3 months after end of intervention

  • Change in Mindful Attention Awareness Scale-Adolescent (MAAS) score

    from baseline to within one month after end of intervention

  • +13 more secondary outcomes

Study Arms (1)

mind-body-skills intervention

EXPERIMENTAL

mind-body-skills group intervention offered weekly for 10 weeks

Behavioral: mind-body-skills group

Interventions

mind-body skills group program incorporates meditation, guided imagery, breathing techniques, autogenic training, biofeedback, genograms, and self-expression through words, drawings, and movement

mind-body-skills intervention

Eligibility Criteria

Age13 Years - 17 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Eskenazi Primary Care patients at time of screening
  • years old
  • Diagnosis of depression confirmed by Mini International Neuropsychiatric Interview (MINI) Kid Screen (with adolescent)
  • English speaking
  • Willingness to attend mind body skills group for duration of the intervention (10 sessions over approximately 10 weeks)

You may not qualify if:

  • History of bipolar disorder or psychosis
  • Acute and immediate risk of suicide, determined by clinical assessment
  • Lack of capacity to assent (adolescent) or lack of capacity to consent (parent/guardian)
  • Previous participation by the adolescent in the Eskenazi Mind Body Group intervention

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Eskenazi Health Primary Care

Indianapolis, Indiana, 46254, United States

Location

Related Publications (1)

  • Cunningham LD, Salgado EF, Aalsma MC, Garabrant JM, Staples JK, Gordon JS, Salyers MP. Do adolescents consider mind-body skills groups an acceptable treatment for depression: results from a pilot study. BMC Pediatr. 2021 Oct 27;21(1):475. doi: 10.1186/s12887-021-02942-3.

MeSH Terms

Conditions

DepressionDepressive Disorder

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehaviorMood DisordersMental Disorders

Study Officials

  • Michelle P Salyers, PhD

    Indiana University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

November 21, 2017

First Posted

December 6, 2017

Study Start

January 25, 2018

Primary Completion

September 4, 2019

Study Completion

September 4, 2019

Last Updated

March 10, 2020

Record last verified: 2020-03

Data Sharing

IPD Sharing
Will not share

Locations