Colonoscopic Adenoma and Advanced Neoplasia Detection Rates According to Age

NCT03361904 | Completed

• 1 other identifier: 2016-ADR according to age
• Study Type: observational
• Target: 6,027
• Locations: 0 countries
• Sites: N/A

Brief Summary

Current recommendations for colonoscopy screening programs usually involve patients older than 50 years of age. However, little is known about polyp or adenoma detection rates under 50. We compared these detection rates according to age in a large series of patients in common practice. Methods: All colonoscopies performed in 2016 in our unit were prospectively recorded. We determined adenoma detection rate (ADR), polyp detection rate (PDR), mean number of polyps (MNP), and advanced neoplasia detection rate (ANDR).

Conditions

Colonic Polyp; Colon Adenoma; Colonoscopy; Colon Cancer; Age

Outcome Measures

Primary Outcomes (2)

• Adenoma detection rate according to age

  ADR \<30yo, in 30-34 yo, in 35-39yo, in 40-44yo, in 45-49yo, in 50-54yo, in 55-59yo, in 60-64yo, in 65-69 yo, in 70-74yo, in 75-79yo and \>79yo intervals

  during colonoscopy

• Advanced Neoplasia Detection rate according to age

  ANDR \<30yo, in 30-34 yo, in 35-39yo, in 40-44yo, in 45-49yo, in 50-54yo, in 55-59yo, in 60-64yo, in 65-69 yo, in 70-74yo, in 75-79yo and \>79yo intervals

  during colonoscopy

Secondary Outcomes (6)

• Age

  during colonoscopy

• Gender

  during colonoscopy

• Indication for colonoscopy

  during colonoscopy

• quality of the preparation

  during colonoscopy

• Caecal intubation

  during colonoscopy

Interventions

Colonoscopy PROCEDURE

Total colonoscopy : All consecutive patients who were scheduled for colonoscopy were included. Exclusion criteria were: patients scheduled for partial colonoscopy, interventional colonoscopy (for stent insertion, stenosis dilation).

Eligibility Criteria

• Age: 15 Years - 99 Years
• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

During the study period, 6335 colorectal endoscopic procedures were realized in the endoscopy unit. We excluded 278 sigmoidoscopies and 30 interventional procedures for stent insertion or stenosis dilation. Only diagnostic colonoscopies were recorded, performed in 3308 women (54.9%) and 2719 men (45.1%) with a median age of 57 (range, 15-96: IQR 18).

You may qualify if:

• All consecutive patients who were scheduled for colonoscopy were included.

You may not qualify if:

• patients scheduled for partial colonoscopy, interventional colonoscopy (for stent insertion, stenosis dilation).

Sponsors & Collaborators

• Société Française d'Endoscopie Digestive: lead

MeSH Terms

Conditions

Colonic Polyps; Colonic Neoplasms

Interventions

Colonoscopy

Condition Hierarchy (Ancestors)

Intestinal Polyps; Polyps; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Colorectal Neoplasms; Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases

Intervention Hierarchy (Ancestors)

Endoscopy, Gastrointestinal; Endoscopy, Digestive System; Diagnostic Techniques, Digestive System; Diagnostic Techniques and Procedures; Diagnosis; Endoscopy; Diagnostic Techniques, Surgical; Digestive System Surgical Procedures; Surgical Procedures, Operative; Minimally Invasive Surgical Procedures

Study Officials

• David Karsenti, MD

  Pole Digestif Paris-Bercy

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 7 Days
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: November 28, 2017
• First Posted: December 5, 2017
• Study Start: January 1, 2016
• Primary Completion: December 31, 2016
• Study Completion: December 31, 2016
• Last Updated: December 5, 2017

Record last verified: 2017-12

Data Sharing

• IPD Sharing: Will not share