Comparing Measurements Made in an Incremental Shuttle Walk Test and a Cardiopulmonary Exercise Test in Patients With IPF

NCT03360032 | Unknown

• 1 other identifier: 222072
• Study Type: observational
• Target: 43
• Locations: 1 country
• Sites: 1

Brief Summary

Idiopathic pulmonary fibrosis (IPF) is a chronic and potentially fatal lung disease. As IPF progresses, patients become increasingly breathless with reduced exercise capacity and quality of life. A cardiopulmonary exercise test (CPET) is a gold standard way of assessing patients with IPF. An incremental shuttle walk test is simpler, cheaper, more widely available and anecdotally preferable to CPET. The investigators will compare the measurements made in an ISWT and a CPET in patients with IPF . We aim to determine whether sufficient information can be gathered in an ISWT to negate the need to undertake CPET.

Conditions

Idiopathic Pulmonary Fibrosis

Keywords

Incremental shuttle walk test; Cardiopulmonary exercise test; VO2 peak

Outcome Measures

Primary Outcomes (1)

• VO2 peak

  Maximum oxygen consumption at peak exercise

  Measured and reported at time of test

Secondary Outcomes (1)

• PO2

  Measured and reported at time of test

Study Arms (1)

All participants

All patients will be asked to undertake an incremental shuttle walk test and a cardiopulmonary exercise test and the results will be compared.

Eligibility Criteria

• Age: 16 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients with a confirmed diagnosis of idiopathic pulmonary fibrosis who are under the care of the Respiratory team at University Hospitals Coventry and Warwickshire NHS Trust.

You may qualify if:

• Diagnosis of idiopathic pulmonary fibrosis confirmed by a multi-disciplinary team.
• Aged 16 or over
• Able to give informed consent to take part
• Able to undertake both a cycle ergometry test and an incremental shuttle walk test without needing walking aids

You may not qualify if:

• An inability to give informed consent.
• Taking part in a research project with a potentially research-modifying intervention
• Currently pregnant.
• Currently breastfeeding.
• Unable to perform an incremental shuttle walk test.
• Unable to perform an incremental cycle ergometry test.
• Unable to walk without an aid such as a stick or frame.

Sponsors & Collaborators

• University Hospitals Coventry and Warwickshire NHS Trust: lead

Study Sites (1)

University Hospital

Coventry, Warwickshire, CV2 2DX, United Kingdom

RECRUITING

MeSH Terms

Conditions

Idiopathic Pulmonary Fibrosis

Condition Hierarchy (Ancestors)

Pulmonary Fibrosis; Lung Diseases, Interstitial; Lung Diseases; Respiratory Tract Diseases

Study Officials

• David Parr

  University Hospitals Coventry and Warwickshire NHS Trust

  PRINCIPAL INVESTIGATOR

Central Study Contacts

David Parr

CONTACT

02476 967697; david.parr@uhcw.nhs.uk

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 27, 2017
• First Posted: December 2, 2017
• Study Start: January 10, 2018
• Primary Completion: April 1, 2020
• Study Completion: April 1, 2020
• Last Updated: September 27, 2019

Record last verified: 2019-09

Data Sharing

• IPD Sharing: Will not share

Locations

GB (1)