NCT03359889

Brief Summary

This program will be initiated after the commercial availability of PraxbindTM in India. It will include patients administered with PraxbindTM into the surveillance program after commercial availability in 2 years at selected centres approved by the regulatory authority.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Dec 2018

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 28, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

December 2, 2017

Completed
1.1 years until next milestone

Study Start

First participant enrolled

December 26, 2018

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 13, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 13, 2020

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

February 16, 2021

Completed
Last Updated

August 25, 2023

Status Verified

August 1, 2023

Enrollment Period

1 year

First QC Date

November 28, 2017

Results QC Date

January 13, 2021

Last Update Submit

August 10, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Number of Participants With Suspected Adverse Drug Reactions (ADRs) and Fatal Adverse Events (AEs)

    Number of participants with suspected adverse drug reactions (ADRs) and fatal adverse events (AEs) occurring within 7 days after Praxbind® administration.

    Up to 7 days following treatment.

Secondary Outcomes (1)

  • Percentage of Patients Who Received Praxbind® Either for Emergency Surgery/Urgent Procedures or for Life-threatening or Uncontrolled Bleeding

    Data collected from patients who had been treated with Praxbind® within 2 years of the commercial availability of Praxbind®.

Study Arms (1)

patients administered with PraxbindTM

Drug: PraxbindTM

Interventions

Drug

Also known as: PRAXBIND, Praxbind, Prizbind
patients administered with PraxbindTM

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients, who receive PraxbindTM prescribed as per the approved label

You may qualify if:

  • \- Patients treated with Pradaxa (dabigatran etexilate) capsules with requirement of rapid reversal of the anticoagulant effects of dabigatran: For emergency surgery/urgent procedures (or) In life-threatening or uncontrolled bleeding
  • \- Written informed consent in accordance with International Conference on Harmonization Good Clinical Practice (GCP) guidelines and local legislation and/or regulations

You may not qualify if:

  • Participation in a PraxbindTM clinical trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Mazumdar Shaw Medical centre

Bangalore, 560099, India

Location

Columbia Asia Referral Hospital

Bengaluru, 560055, India

Location

Care Hospital

Hyderabad, 500034, India

Location

MeSH Terms

Conditions

Thromboembolism

Interventions

idarucizumab

Condition Hierarchy (Ancestors)

Embolism and ThrombosisVascular DiseasesCardiovascular Diseases

Results Point of Contact

Title
Boehringer Ingelheim, Call Center
Organization
Boehringer Ingelheim

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 28, 2017

First Posted

December 2, 2017

Study Start

December 26, 2018

Primary Completion

January 13, 2020

Study Completion

January 13, 2020

Last Updated

August 25, 2023

Results First Posted

February 16, 2021

Record last verified: 2023-08

Locations