NCT03356847

Brief Summary

A good efficacy as well as good rotary stability is expected with the ocular implant.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 29, 2017

Completed
Same day until next milestone

Study Start

First participant enrolled

September 29, 2017

Completed
2 months until next milestone

First Posted

Study publicly available on registry

November 29, 2017

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 11, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 11, 2018

Completed
Last Updated

August 2, 2018

Status Verified

November 1, 2017

Enrollment Period

10 months

First QC Date

September 29, 2017

Last Update Submit

August 1, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Rotational stability of SISA monofocal implant following cataracts surgery

    rotation in degrees measured by Labview software

    4 Months

Secondary Outcomes (19)

  • Rotational stability of SISA monofocal implant following cataracts surgery

    Day 0

  • Rotational stability of SISA monofocal implant following cataracts surgery

    Day 7

  • Rotational stability of SISA monofocal implant following cataracts surgery

    1 Month

  • Centering of SISA monofocal implant

    Day 0

  • Centering of SISA monofocal implant

    Day 7

  • +14 more secondary outcomes

Study Arms (1)

SISA implant

EXPERIMENTAL
Device: Fitting of ocular implant

Interventions

Removal of natural lens and replacement with a SISA monofocal intraocular implant

SISA implant

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • The patient must have given their free and informed consent and signed the consent form
  • The patient must be a member or beneficiary of a health insurance plan
  • The patient must be available for 6 months follow-up
  • The patient it aged at least 18 years
  • Patient requires surgery for cataracts with removal of the opacified natural lens and replacement with the SISA implant, according to standard procedure
  • The surgery is elective
  • The patient has clear and non-pathological corneas
  • The patient needs an implant strength (LIO) between +10D and +30D
  • Corneal astigmatism less than or equal to 1.50D in the eye to be operated (or cataract eye

You may not qualify if:

  • The patient is under safeguard of justice or state guardianship
  • The subject refuses to sign the consent
  • It is impossible to give the subject informed information
  • The patient is pregnant or breastfeeding
  • The patient has other ocular comorbidities with poor visual acuity prognosis postoperatively
  • Previous ocular trauma or surgery
  • Dilation of the pupil \<7mm with mydriatic drugs
  • Implantation with a rhexis that does not cover the optic of the implant by more than 1 cadranel

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU Nimes

Nîmes, 30029, France

Location

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 29, 2017

First Posted

November 29, 2017

Study Start

September 29, 2017

Primary Completion

July 11, 2018

Study Completion

July 11, 2018

Last Updated

August 2, 2018

Record last verified: 2017-11

Locations