NCT03354078

Brief Summary

Only a small number of research studies evaluated the impact of various subcutaneous tissue and skin closure methods at cesarean section. In a meta-analysis a major decline in incision site rupture was revealed when suturing the subcutaneous tissue in women with a subcutaneous depth \>2 cm.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 18, 2017

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2017

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

November 19, 2017

Completed
4 days until next milestone

Study Completion

Last participant's last visit for all outcomes

November 23, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 27, 2017

Completed
Last Updated

April 5, 2022

Status Verified

April 1, 2022

Enrollment Period

5 months

First QC Date

November 19, 2017

Last Update Submit

April 2, 2022

Conditions

Keywords

Cesarean sectionWound infectionGapping

Outcome Measures

Primary Outcomes (1)

  • The number of participants who passed without postoperative complications

    Describes how many participant willnot complain from wound seroma , wound erythema and wound infection

    one month post cesarean section

Study Arms (2)

interrupted sutures group

ACTIVE COMPARATOR

This group in which closure of the subcutaneous layer is closed by interrupted sutures

Procedure: interrupted suturesProcedure: continous sutures

Continous sutures group

ACTIVE COMPARATOR

subcutanous tissue layer is closed by continous sutures in this group

Procedure: interrupted suturesProcedure: continous sutures

Interventions

The way of closing subcutaneous tissue either by interrupted

Continous sutures groupinterrupted sutures group

The way of closure of subcutanous tissue is by continous sutures

Continous sutures groupinterrupted sutures group

Eligibility Criteria

Age18 Years - 40 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility DetailsPregnant females
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • All patients included in this research BMI ≥ 30, First cesarean section performed, no medical disorders with pregnancy e.g DM, HTN. All patients were subjected to full history taking, examination.
  • depth of subcutaneous tissue estimated by a special device used (sterilized operative ruler). number of sutures estimation

You may not qualify if:

  • The following patients were excluded BMI \<30, Previous CS, DM with pregnancy, HTN with pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Algazeerah

Giza, Egypt

Location

Related Publications (1)

  • Alalfy M, Elgazzar A, Fares T, Nagy O, Ellithy A, Lasheen Y, Kamel A, Soliman M, Hassan A, Samy A, Taher AM, Ogila AI, Saad H, Salah H, Ramadan M, Nabil M, Hatem DL, Fikry M. Effect of subcutaneous tissue closure technique in cesarean section on postoperative wound complications in obese Egyptian women. J Matern Fetal Neonatal Med. 2019 Aug;32(15):2452-2459. doi: 10.1080/14767058.2018.1438399. Epub 2018 Feb 20.

MeSH Terms

Conditions

Wound Infection

Condition Hierarchy (Ancestors)

Infections

Study Officials

  • Mahmoud Alalfy, M.s.c

    Algazeerah hospital -Location (Giza -Egypt )

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 19, 2017

First Posted

November 27, 2017

Study Start

June 18, 2017

Primary Completion

November 1, 2017

Study Completion

November 23, 2017

Last Updated

April 5, 2022

Record last verified: 2022-04

Locations