The Study of Post-operation Delirium and Prognosis of Cardiac Surgery Patients
the Effect of Quantitative Electroencephalogram (qEEG) in Predictive of Post-operation Delirium and Prognosis of Cardiac Surgery Patients
1 other identifier
observational
56
0 countries
N/A
Brief Summary
Delirium is the most common neurological complication of cardiac surgery patients and associated with poor prognosis. In recent years, the important role of quantitative electroencephalogram (qEEG) in brain function monitoring is becoming increasingly prominent. The purpose of this study is to evaluate the effect of qEEG in predictive of post-operation delirium and prognosis of cardiac surgery patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Dec 2017
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 14, 2017
CompletedFirst Posted
Study publicly available on registry
November 24, 2017
CompletedStudy Start
First participant enrolled
December 1, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 30, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
August 31, 2018
CompletedNovember 24, 2017
November 1, 2017
7 months
November 14, 2017
November 21, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
amplitude integrated electroencephalogram (aEEG)
the electroencephalogram amplitude of cardiac surgery patients assessed by quantitative electroencephalogram when admitted to intensive care unit
24 hours
Secondary Outcomes (12)
alpha frequency band energy
24 hours
beta frequency band energy
24 hours
theta frequency band energy
24 hours
delta frequency band energy
24 hours
alpha variability
24 hours
- +7 more secondary outcomes
Study Arms (2)
Delirium Group
The cardiac surgery patients with delirium receive the quantitative electroencephalogram (qEEG) monitoring within 1 hour when they admitted to ICU
Non-delirium Group
The cardiac surgery patients without delirium receive the quantitative electroencephalogram (qEEG) monitoring within 1 hour when they admitted to ICU
Interventions
the patients receive the quantitative electroencephalogram (qEEG) monitoring within 1 hour when they admitted to ICU
Eligibility Criteria
Adult patients receiving cardiac surgery
You may qualify if:
- The patients of cardiac surgery aged ≥18 years
- Signed informed consent
You may not qualify if:
- Patients with a history of any neurologic and psychiatric disease
- Cognitive disorder
- Stroke history in three years
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Guo Z, Wan W, Liu W, Liu L, Yang Y, Yang C, Cui X. Quantitative electroencephalography predicts postoperative delirium in adult cardiac surgical patients from a prospective observational study. Sci Rep. 2024 Dec 28;14(1):31101. doi: 10.1038/s41598-024-82422-7.
PMID: 39730694DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Liu Wenxue, master
Southeast University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- professor
Study Record Dates
First Submitted
November 14, 2017
First Posted
November 24, 2017
Study Start
December 1, 2017
Primary Completion
June 30, 2018
Study Completion
August 31, 2018
Last Updated
November 24, 2017
Record last verified: 2017-11