Ewha Birth and Growth Study (Birth Cohort)

NCT03351595 | Completed

• 1 other identifier: EWCS
• Study Type: observational
• Target: 940
• Locations: 1 country
• Sites: 1

Brief Summary

The Ewha Birth and Growth Study is a prospective birth cohort established at Ewha Womans University Mokdong Hospital in Seoul, Republic of Korea. Pregnant women were recruited between 2001 and 2006, and their offspring were followed longitudinally from birth through childhood, adolescence, and young adulthood.

Conditions

Pediatric Health; Growth & Development; Cardiometabolic Health

Keywords

Growth pattern; Environmental and prenatal exposure; Birth cohort; Longitudinal study; Life-course approach

Outcome Measures

Primary Outcomes (1)

• Physical growth assessed by anthropometric measurements

  Anthropometric measurements were obtained during scheduled follow-up examinations to assess longitudinal physical growth. Participants received individualized health examination results following the assessments.

  At 3 and 5 years of age; annually from 7 through 12 years of age; at 13 to 15 years of age; and at 19 years of age

Secondary Outcomes (2)

• Blood pressure assessed during follow-up examinations

  At 3 and 5 years of age; annually from 7 through 12 years of age; at 13 to 15 years of age; and at 19 years of age

• Metabolic biomarkers assessed during follow-up examinations

  At 3 and 5 years of age; annually from 7 through 12 years of age; at 13 to 15 years of age; and at 19 years of age

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Pregnant women recruited during prenatal care and their offspring followed longitudinally from birth through young adulthood.

You may qualify if:

• Pregnant women who received prenatal care between 24 and 28 weeks of gestation and were enrolled between 2001 and 2006.
• Individuals who could participate in scheduled follow-up examinations and comply with the study requirements.

You may not qualify if:

• \- Individuals considered unable to participate in the study procedures for other reasons, based on the investigator's judgement.

Sponsors & Collaborators

• Ewha Womans University: lead
• National Research Foundation of Korea: collaborator

Study Sites (1)

Ewha Womans University Seoul Hospital

Seoul, South Korea

Location

Related Publications (1)

• Lee HA, Park B, Min J, Choi EJ, Kim UJ, Park HJ, Park EA, Cho SJ, Kim HS, Lee H, Kim YJ, Hong YS, Kim EJ, Ha EH, Park H. Cohort profile: the Ewha Birth and Growth Study. Epidemiol Health. 2021;43:e2021016. doi: 10.4178/epih.e2021016. Epub 2021 Feb 22.

  PMID: 33677859 RESULT

Biospecimen

Retention: SAMPLES WITH DNA

Biospecimen Description: blood samples (3 mL EDTA whole blood and 5 mL serum) and urine samples.

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 18, 2017
• First Posted: November 24, 2017
• Study Start: September 1, 2001
• Primary Completion: August 1, 2026
• Study Completion: August 1, 2026
• Last Updated: September 21, 2026

Record last verified: 2026-09

Locations

KR (1)