Effectiveness of Contingency Management in the Treatment of Crack Addiction in Brazil

NCT03345394 | Completed Results

• 1 other identifier: FAPESP 2017/05371-8
• Study Type: interventional
• Target: 98
• Locations: 1 country
• Sites: 1

Brief Summary

Crack addiction has become a severe public health problem in Brazil. Crack users present elevated prevalence rates of psychiatric comorbidities, sexual transmitted infections and unemployment with high probability of living or have lived in the streets, history of incarceration and engagement in illegal activities. For the last 20 years a treatment called Contingency Management (CM) have achieved the best results regarding reduction of substance use, promotion of abstinence, treatment attendance and retention in treatment. The first CM study conducted in Brazil advocates for the efficacy of CM on all of these outcomes, suggesting that CM can be effective in a Brazilian population of crack users.

Conditions

Substance Use Disorders; Contingency Management; Addiction, Cocaine

Keywords

crack cocaine; contingency management; ambulatory treatment; Brazil

Outcome Measures

Primary Outcomes (2)

• Pattern of Crack Cocaine Use

  Percentage of negative crack cocaine urine samples submitted during the 12 weeks of treatment

  12 weeks

• Promotion of Continuous Crack Cocaine Abstinence

  Longest duration of continuous abstinence achieved (in weeks)

  12 weeks

Secondary Outcomes (1)

• Treatment Retention

  12 weeks

Study Arms (2)

Standard Treatment

ACTIVE COMPARATOR

12 weeks of standard treatment offered by Unidade Recomeço Helvétia treatment program

Behavioral: Standard treatment

Contingency Management

EXPERIMENTAL

12 weeks of standard treatment offered at Unidade Recomeço Helvétia treatment program associated with Contingency Management

Behavioral: Contingency Management

Interventions

Contingency Management BEHAVIORAL

Participants will receive vouchers with monetary value for submitting crack cocaine negative urine samples

Contingency Management

Standard treatment BEHAVIORAL

Participants will receive the standard treatment offered at Unidade Recomeço Helvétia treatment program

Standard Treatment

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• DSM-V diagnose for crack cocaine use disorder

You may not qualify if:

• being under 18 years old

Sponsors & Collaborators

• Federal University of São Paulo: lead
• Washington State University: collaborator

Study Sites (1)

Unidade Recomeço Helvétia

São Paulo, São Paulo, 01215-010, Brazil

Location

MeSH Terms

Conditions

Substance-Related Disorders; Cocaine-Related Disorders

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders

Results Point of Contact

• Title: Dr. André Miguel
• Organization: Federal University of Sao Paulo

aqcmiguel@gmail.com

+55 11 965884111

Study Officials

• Andre M de Queiroz Constantino Miguel, PhD

  Federal University of São Paulo

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Masking Details: researchers had no contact with participants during the 12 week trial
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Single-blind randomized controlled trial

Study Record Dates

• First Submitted: November 14, 2017
• First Posted: November 17, 2017
• Study Start: December 1, 2017
• Primary Completion: December 1, 2020
• Study Completion: December 1, 2020
• Last Updated: April 8, 2021
• Results First Posted: April 8, 2021

Record last verified: 2021-03

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)