NCT03344471

Brief Summary

Each year in France, between 50,000 and 60,000 children are born prematurely (\< 37 weeks of amenorrhea). Literature has shown that preterm deliveries can be associated with the development of PTSD (Post-Traumatic Stress Disorder) in mothers. Around ¼ of women suffer from a PTSD after giving birth prematurely. Moreover, studies highlighted the consequences of a PTSD on the child-mother relationship. Beyond the importance of early detection, it could be important to predict factors that make women more likely to develop a PTSD. This study will focus on personal factors (5 dimensions of personality). Our hypothesis is that personality traits are associated with the likeliness of developing a PTSD after a preterm delivery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2017

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 14, 2017

Completed
3 days until next milestone

First Posted

Study publicly available on registry

November 17, 2017

Completed
26 days until next milestone

Study Start

First participant enrolled

December 13, 2017

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 14, 2019

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 14, 2019

Completed
Last Updated

February 18, 2022

Status Verified

February 1, 2022

Enrollment Period

1.4 years

First QC Date

November 14, 2017

Last Update Submit

February 17, 2022

Conditions

Keywords

preterm deliveryPTSDprematuritybirthpersonality

Outcome Measures

Primary Outcomes (2)

  • PPQ (Perinatal PTSD Questionnaire)

    The PPQ is widely used to assess symptoms of PTSD after preterm delivery.

    Day 0

  • NEO-FFI

    self-administered questionnaire used to measure 5 dimensions of personality (Neuroticism, Extraversion, Openness, Agreeability and Conscientiousness)

    Day 0

Study Arms (2)

women with PTSD after preterm deliver

OTHER
Other: Passation of questionnaires

women without PTSD after preterm deliver

OTHER
Other: Passation of questionnaires

Interventions

Specific questionnaires (Perinatal PTSD Questionnaire evaluating the Post-Traumatic Stress Disorder) and (NEO-FFI evaluating personality)

women with PTSD after preterm deliverwomen without PTSD after preterm deliver

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • mothers who have given birth prematurely (\<33 weeks of amenorrhea)
  • mothers who speak French fluently
  • mothers consenting to participate to the study
  • mothers enrolled in the national healthcare insurance program
  • mothers older than 18 years

You may not qualify if:

  • mothers with acute or chronic psychotic disorders,
  • mothers with alcohol and/or drug abuse or dependence

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Damien JOLLY

Reims, France

Location

MeSH Terms

Conditions

Premature BirthStress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Obstetric Labor, PrematureObstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesStress Disorders, TraumaticTrauma and Stressor Related DisordersMental Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 14, 2017

First Posted

November 17, 2017

Study Start

December 13, 2017

Primary Completion

May 14, 2019

Study Completion

December 14, 2019

Last Updated

February 18, 2022

Record last verified: 2022-02

Locations