NCT03343730

Brief Summary

the purpose of this study is to examine whether the deployment of a non-mydriatic color fundus camera in a rural prime care setting is feasible and improves the detection rate of diabetic retinopathy in patients where adherence rates with recommended ophthalmology screening is low.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 13, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 17, 2017

Completed
3 months until next milestone

Study Start

First participant enrolled

February 27, 2018

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2018

Completed
Last Updated

July 11, 2018

Status Verified

July 1, 2018

Enrollment Period

7 months

First QC Date

November 13, 2017

Last Update Submit

July 10, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Rate of Diabetic Retinopathy Detection

    This study will examine the rate of detection of diabetic retinopathy using an in-clinic retinal camera and standard referral to eye care professional for dilated eye exam

    3 months

Study Arms (2)

Non-mydriatic color fundus photography

EXPERIMENTAL

All participants will receive Non-mydriatic color fundus photography with the RetinaVue camera at an already scheduled annual physical exam or follow up clinic visit with their primary care provider (PCP).

Diagnostic Test: Non-mydriatic color fundus photography with the RetinaVue camera

Standard of Care (Control)

ACTIVE COMPARATOR

All patients will also receive a referral for a dilated eye exam with an eye care professional. A yearly dilated exam as referred by the PCP.

Diagnostic Test: Referral for dilated eye exam with an eye care professional

Interventions

This hand-held device allows the primary care physician to capture an image of the patient's retina and transmit the image to a board-certified ophthalmologist for interpretation.

Non-mydriatic color fundus photography

All patients will be given a referral to an eye care professional for a routine, dilated, diabetic eye exam.

Standard of Care (Control)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age ≥ 18 years
  • Type II diabetes without documented diabetic retinopathy

You may not qualify if:

  • Documented ocular pathology that may interfere with image acquisition (i.e. high grade cataract)
  • Macular pathology (i.e. macular degeneration, cystoid macular edema, central serous retinopathy)
  • Inability to attain analyzable RetinaVue image due to ocular pathology or other conditions (such as tremors limiting ability to maintain stable head for image)
  • Acute or emergent ocular pathology that requires urgent assessment by an eye care professional as identified by the RetinaVue camera interpretation report
  • Seen within the last 11 months for a diabetic eye exam.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bassett Medical Center

Cooperstown, New York, 13326, United States

RECRUITING

MeSH Terms

Conditions

Diabetic Retinopathy

Condition Hierarchy (Ancestors)

Retinal DiseasesEye DiseasesDiabetic AngiopathiesVascular DiseasesCardiovascular DiseasesDiabetes ComplicationsDiabetes MellitusEndocrine System Diseases

Study Officials

  • james Dalton, MD

    Bassett Medical Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

jennifer Victory, RN

CONTACT

Julie Tirrell, RN

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
SCREENING
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Attending Physician - Primary Care

Study Record Dates

First Submitted

November 13, 2017

First Posted

November 17, 2017

Study Start

February 27, 2018

Primary Completion

October 1, 2018

Study Completion

October 1, 2018

Last Updated

July 11, 2018

Record last verified: 2018-07

Locations