The Diagnostic Value of Acupoint Sensitization Based on Stable Angina Pectoris

NCT03341663 | Completed

• 1 other identifier: 201781590955
• Study Type: observational
• Target: 183
• Locations: 1 country
• Sites: 1

Brief Summary

Investigators adopt cross-sectional study design to carry out the exemplary research in the aspects of disease diagnosis.This study is designed to confirm the hypothesis "acupoint sensitization is associated with a severity of angina pectoris, which may contribute to the diagnosis of stable angina pectoris". After the eligible participants recruited in group, the coronary artery lesions will be evaluated through coronary angiography and the Canadian Cardiovascular Society(CCS) angina pectoris classification will also be evaluated at the same time. The degree of acupoint sensitization will be tested by the electronic Von Frey instrument by one professional acupuncturist with total 12 acupoints, including Shenmen,Yinxi, Shaohao,Jiquan,Neiguan, Ximen, Quze, Shanzhong, Juque, Jueyinyu, Xinyu, Duyu. Analysis were conducted to explore relationships between the degree of acupoint sensitization, the degree of coronary artery stenosis and CCS angina pectoris classification. Diagnostic value will be further analyzed in the final step.

Conditions

Stable Angina Pectoris; Acupoint Sensitization; Correlation Analysis; Diagnostic Value

Keywords

Stable Angina Pectoris; Acupoint sensitization; Correlation analysis; Diagnostic value

Outcome Measures

Primary Outcomes (3)

• The degree of acupoint sensitization

  The value will be obtained through the electronic Von Frey instrument

  About 1 hour

• The degree of coronary artery stenosis

  Data will be obtained through coronary angiography

  About 2 hours

• Canadian Cardiovascular Society angina pectoris classification

  About 1 hours

Interventions

Coronary angiography,Canadian Cardiovascular Society angina pectoris classification for the severity of angina and electronic Von Frey instrument for testing the degree of acupoint sensitization COMBINATION_PRODUCT

All the interventions were tested for only once

Eligibility Criteria

• Age: 35 Years - 80 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients were recruited from the department of cardiology in the West China Hospital of Sichuan University

You may qualify if:

• Patients meet the diagnostic criteria of ACC/AHA angina pectoris of coronary heart disease
• The frequency of angina attacks were greater or equal to twice a week over the previous 3 months
• Patients agree to do coronary angiography examination and sign the informed consent.

You may not qualify if:

• People with mental disabilities and intelligent obstacle
• Patients who can't accomplish the detection of acupoint sensitization
• Patients with allergic condition, especially the contrast media
• Patients with acute myocardial infarction, unstable angina, during arrhythmia and serious diseases which can affect the blood supply of myocardial
• Patients with skin or peripheral nerve paresthesia, pain or the detect area of skin ulcerate
• Pregnant or lactating women
• Patients who undergoing other clinical trials

Sponsors & Collaborators

• West China Hospital: lead

Study Sites (1)

The West China Hospital of Sichuan university

Chengdu, Sichuan, 610041, China

Location

MeSH Terms

Conditions

Angina, Stable

Condition Hierarchy (Ancestors)

Angina Pectoris; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Chest Pain; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director

Study Record Dates

• First Submitted: October 26, 2017
• First Posted: November 14, 2017
• Study Start: December 6, 2017
• Primary Completion: October 28, 2018
• Study Completion: November 29, 2018
• Last Updated: May 9, 2024

Record last verified: 2024-05

Locations

CN (1)