NCT03326479

Brief Summary

This repository is a multi-center, outcomes study designed to retrospectively collect data on the demographics, presentation, diagnosis, treatment, cost of associated care, quality of life, and outcomes of subjects utilizing Caris Molecular Intelligence® (CMI) Services for the treatment of cancer. Prior to enrolling a subject, the subject's physician will have made the independent decision whether or not to utilize the drug associations provided by CMI and made clinical treatment choices as appropriate. Thus, data captured and reported provides a "real world" perspective on diagnosis, treatment, cost, and outcomes.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
10,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2016

Longer than P75 for all trials

Geographic Reach
1 country

3 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 30, 2016

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

October 19, 2017

Completed
12 days until next milestone

First Posted

Study publicly available on registry

October 31, 2017

Completed
5.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2023

Completed
Last Updated

October 31, 2017

Status Verified

October 1, 2017

Enrollment Period

6.1 years

First QC Date

October 19, 2017

Last Update Submit

October 26, 2017

Conditions

Keywords

Molecular ProfilingBiomarker AnalysisOutcomes Database

Outcome Measures

Primary Outcomes (1)

  • Data Gathering

    Documentation of the frequency of specific clinical events in relation to diagnosis, treatments and outcomes provided

    5 years per patient

Study Arms (1)

Retrospective

Subject who have previously had MI Profiling performed prior to 11/11/2016 are eligible for this study. No drug intervention is required for this study.

Diagnostic Test: Caris Molecular Intelligence Profile

Interventions

A comprehensive biomarker testing

Retrospective

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Subject's who have had CMI testing prior to 11/11/2016 at one of the participating POA sites.

You may qualify if:

  • Subject' s age must be greater than or equal to 18 years and must have received CMI testing prior to the initial protocol IRB submission date of November 11, 2016.

You may not qualify if:

  • Due to the complexity of state and federal requirements governing the participation of prisoners in research, prisoners-patients shall not be approached for participation.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Highlands Oncology Group

Fayetteville, Arkansas, 72703, United States

Location

Nebraska Cancer Specialists

Omaha, Nebraska, 68130, United States

Location

The University of Texas Health Science Center at San Antonio

San Antonio, Texas, 78229, United States

Location

MeSH Terms

Conditions

Neoplasms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 19, 2017

First Posted

October 31, 2017

Study Start

November 30, 2016

Primary Completion

January 1, 2023

Study Completion

January 1, 2023

Last Updated

October 31, 2017

Record last verified: 2017-10

Locations