NCT03321266

Brief Summary

The study is a retrospective review of the use of the Biodesign® Fistula Plug (C-FPS-\[X\]). A total of 73 patients will be enrolled who have had a fistula plug placed to treat anorectal fistulas and will therefore be eligible for statistical analysis.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
79

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Nov 2017

Geographic Reach
2 countries

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 20, 2017

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 25, 2017

Completed
1 month until next milestone

Study Start

First participant enrolled

November 30, 2017

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 29, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 29, 2019

Completed
Last Updated

September 25, 2019

Status Verified

September 1, 2019

Enrollment Period

1.7 years

First QC Date

October 20, 2017

Last Update Submit

September 24, 2019

Conditions

Keywords

Fistula plug

Outcome Measures

Primary Outcomes (1)

  • Rate of fistula closure

    Absence of drainage from the external fistula opening with complete epithelialization of the external fistula opening upon clinical exam.

    up to 2 years

Study Arms (1)

Patients treated for a anorectal fistula

Patients who were treated for a anorectal fistula with a Biodesign Fistula plug

Device: Cook Biodesign® Fistula Plug

Interventions

The Cook Biodesign® Fistula Plug is for implantation to reinforce soft tissue for repair of Anorectal fistulas.

Patients treated for a anorectal fistula

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients implanted with the Cook Biodesign Fistula Plug at each of the participating institutions through 31 Dec 2016 will be included in the retrospective data collection regardless of outcome. A patient must have at least one follow-up visit.

You may qualify if:

  • Patients who have had surgery to treat anorectal fistula where the Biodesign® Fistula Plug was placed during the procedure

You may not qualify if:

  • Patients not receiving the Biodesign® Fistula Plug for treatment of their anorectal fistula

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

University of Louisville School of Medicine

Louisville, Kentucky, 40202, United States

Location

Our Lady of the Lake Regional Medical Center

Baton Rouge, Louisiana, 70808, United States

Location

University Surgical Associates

Providence, Rhode Island, 02904, United States

Location

St Josef's Hospital

Wiesbaden, 65189, Germany

Location

MeSH Terms

Conditions

Rectal Fistula

Condition Hierarchy (Ancestors)

Intestinal FistulaDigestive System FistulaDigestive System DiseasesIntestinal DiseasesGastrointestinal DiseasesRectal DiseasesFistulaPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Study Officials

  • Adal Saeed, MD

    St Josef's Hospital, Wiesbaden

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 20, 2017

First Posted

October 25, 2017

Study Start

November 30, 2017

Primary Completion

August 29, 2019

Study Completion

August 29, 2019

Last Updated

September 25, 2019

Record last verified: 2019-09

Locations