Impact of Neurological Diseases on the Prognosis of Bullous Pemphigoid: A Retrospective Study of 178 Patients

NCT03320798 | Completed

• 1 other identifier: 2016Ao004
• Study Type: observational
• Target: 178
• Locations: 1 country
• Sites: 1

Brief Summary

Bullous pemphigoid affects mainly elderly patients. It is often associated with neurologic disorders, which represent a major risk factor of the disease

Conditions

Bullous Pemphigoid

Keywords

Bullous pemphigoid; neurologic disorders

Outcome Measures

Primary Outcomes (1)

• neurological disease

  neurological disease are dementia (Alzheimers disease or other dementia), Parkinson's syndrome and stroke. Diagnosis of dementia was carried out in several ways: after examination by a neurologist or geriatrician, when the Mini Mental State was less than or equal to 17 or in the presence of a demonstrated and clinically evident dementia.

  Day 0

Study Arms (1)

group "Bullous pemphigoid"

Patients consulting at dermatology department of Reims Teaching Hospital for bullous pemphigoid between 1997 and 2011.

Other: Data record

Interventions

Data record OTHER

group "Bullous pemphigoid"

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients presenting bullous pemphigoid and consulting at dermatology department of Reims Teaching Hospital (France) between 1997 and 2011.

You may qualify if:

• patients presenting bullous pemphigoid using the following criteria: clinical features typical of BP with presence of at least three out of four well-established criteria of Vaillant et al., subepidermal blister on skin biopsy and deposits of IgG and/or C3 in a linear pattern along the epidermal basement membrane zone by direct IF
• patients consulting at dermatology department of Reims Teaching Hospital (France) between 1997 and 2011

Sponsors & Collaborators

• CHU de Reims: lead

Study Sites (1)

Damien JOLLY

Reims, France

Location

MeSH Terms

Conditions

Pemphigoid, Bullous; Nervous System Diseases

Interventions

Electronic Health Records

Condition Hierarchy (Ancestors)

Skin Diseases, Vesiculobullous; Skin Diseases; Skin and Connective Tissue Diseases; Autoimmune Diseases; Immune System Diseases

Intervention Hierarchy (Ancestors)

Medical Records Systems, Computerized; Medical Records; Records; Data Collection; Epidemiologic Methods; Investigative Techniques; Organization and Administration; Health Services Administration; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 23, 2017
• First Posted: October 25, 2017
• Study Start: October 1, 2013
• Primary Completion: October 1, 2014
• Study Completion: March 1, 2015
• Last Updated: October 25, 2017

Record last verified: 2017-10

Locations

FR (1)