Genetic Basis of Pacing-induced Cardiomyopathy
Genetic Basis of Pacing-Induced Cardiomyopathy
1 other identifier
observational
153
1 country
1
Brief Summary
The purpose of this study is to collect a saliva sample from patients with a pacemaker to study genes involved in cardiomyopathy, a condition where the heart muscle is abnormal.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Oct 2017
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 16, 2017
CompletedStudy Start
First participant enrolled
October 16, 2017
CompletedFirst Posted
Study publicly available on registry
October 23, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 19, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
June 19, 2025
CompletedJune 22, 2025
June 1, 2025
7.7 years
October 16, 2017
June 19, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Number of participants with genotype frequency
Number of participants with genotype frequency based on genetic testing of saliva samples
through study completion, an average of 1 year
Study Arms (2)
Saliva - cardiomyopathy
Saliva sample for genetic testing from subjects who developed cardiomyopathy
Saliva - no cardiomyopathy
Saliva sample for genetic testing from subjects who do not have cariomyopathy
Interventions
Extract sample of saliva only once
Eligibility Criteria
Patients seen at Robert Packer Hospital, Sayre, PA
You may qualify if:
- Patients who have been assessed for cardiomyopathy
You may not qualify if:
- Patients who do not have adequate follow up care to determine if they do or do not have cardiomyopathy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Robert Packer Hospital
Sayre, Pennsylvania, 18840, United States
Biospecimen
Saliva
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Pramod Deshmukh, MD
The Guthrie Clinic
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 16, 2017
First Posted
October 23, 2017
Study Start
October 16, 2017
Primary Completion
June 19, 2025
Study Completion
June 19, 2025
Last Updated
June 22, 2025
Record last verified: 2025-06
Data Sharing
- IPD Sharing
- Will not share