Nutritional Impact of a Project on Food Security and Nutrition in Children Receiving Micronutrient Powders in Colombia

NCT03313089 | Completed

• 1 other identifier: 37460
• Study Type: observational
• Target: 112
• Locations: 1 country
• Sites: 1

Brief Summary

The effectiveness of micronutrient powders or MNP as a strategy for the prevention of micronutrient deficiencies has been described in the literature. However, few studies have shown the impact of the inclusion of other simultaneous actions on the different dimensions of food and nutritional security (as in the case of the project "Papas más nutritivas") that will contribute to the improvement of nutritional status, obtaining potentially greater benefits. The objective is to establish the existence of difference in hemoglobin values (and other biochemical parameters as secondary outcomes) among children aged 6 months to 5 years who receive home fortification with micronutrient powders (MNP) belonging to the project "Papas más nutritivas", and children with home fortification with MNP but not belonging to the project.

Conditions

Hemoglobin; Anemia

Keywords

micronutrient powders; spinkles; nutrition; food security program; nutritional program; hemoglobin; anemia

Outcome Measures

Primary Outcomes (1)

• Change in hemoglobin concentration

  g/dL

  Baseline and after 12 months approximately

Secondary Outcomes (4)

• Vitamin A (change in serum retinol concentration)

  Baseline and after 12 months approximately

• Change in zinc concentration

  Baseline and after 12 months approximately

• Change in transferrin concentration

  Baseline and after 12 months approximately

• Change in ferritin concentration

  Baseline and after 12 months approximately

Study Arms (2)

PSAN + MNP

PSAN ("Papas más nutritivas" project) + MNP (micronutrients powders): Children of the families beneficiaries of Community Schools of Family Agriculture of the municipalities of Cumbal, Carlosama Guachucal and Túquerres, who are part of the project "Papas más nutritivas" and exposed to project activities in which they work on topics related to food and nutritional security, equity and gender, production and entrepreneurship, Additionally, the home fortification with MNP that is 12 months in total approximately, will be made 2 deliveries of 60 doses (specified in the "MNP only" group). After the delivery of MNP, advising, measurements of weight and height, clarification of doubts regarding fortification with MNP, nutrition education, and accompaniment by the project staff will take place.

Behavioral: "Papas más nutritivas" (PSAN)

MNP only

Cohort of exposed to MNP (micronutrients powders): Children who will receive MNP delivered through the hospital or institutional health service providers of the municipalities of Guachucal and Carlosama, following the protocol for the home fortification with MNP that is 12 months in total approximately, will be made 2 deliveries of 60 doses: the first period consists of the taking of MNP for 2 months, followed by a rest period of 4 months and continues again by another MNP intake for 2 months and rest for 4 months, and exposed to dissemination of basic information with regard to MNP and monitoring by growth and development that is routinely performed by health staff.

Interventions

"Papas más nutritivas" (PSAN) BEHAVIORAL

Activities of the project "Papas más nutritivas"

PSAN + MNP

Eligibility Criteria

• Age: 6 Months - 5 Years
• Sex: all
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Boys and girls of 6 months to 5 years of age inhabitants of municipalities: Carlosama, Guachucal, Túquerres and Cumbal in the department of Nariño,

You may qualify if:

• Boys and girls of 6 months to 5 years of age receiving home fortification with micronutrient powders.

You may not qualify if:

• Children who are consuming nutritional complements or supplements.
• Children undergoing treatment for anemia or other micronutrient deficiencies.

Sponsors & Collaborators

• Universidad Nacional de Colombia: lead
• International Development Research Centre, Canada: collaborator
• McGill University: collaborator

Study Sites (1)

Universidad Nacional de Colombia

Bogotá, Colombia

Location

Related Publications (16)

• Ministerio De Salud y Protección Social. Estrategia Nacional para la Prevención y Control de las Deficiencias de Micronutrientes en Colombia 2014 - 2021. Bogotá D.C., Colombia. 2015.

  BACKGROUND

• World Health Organization and Food and Agriculture Organization of the United Nations. Guidelines on Food Fortification with Micronutrients. Editado por Lindsay Allen y cols.

  BACKGROUND

• Black R. Micronutrient deficiency--an underlying cause of morbidity and mortality. Bull World Health Organ. 2003;81(2):79. Epub 2003 Mar 25. No abstract available.

  PMID: 12751414 BACKGROUND

• Ministerio de la Protección Social. Instituto Colombiano de Bienestar Familiar. ENSIN 2010- Encuesta Nacional de Situación Nutricional en Colombia 2010. Ed. Bogotá: 2011.

  BACKGROUND

• OMS. Directriz: Uso de micronutrientes en polvo para la fortificación domiciliaria de los alimentos consumidos por lactantes y niños de 6 a 23 meses de edad. Ginebra, Organización Mundial de la Salud, 2012.

  BACKGROUND

• Zlotkin SH, Schauer C, Christofides A, Sharieff W, Tondeur MC, Hyder SM. Micronutrient sprinkles to control childhood anaemia. PLoS Med. 2005 Jan;2(1):e1. doi: 10.1371/journal.pmed.0020001.

  PMID: 15696200 BACKGROUND

• De-Regil LM, Suchdev PS, Vist GE, Walleser S, Pena-Rosas JP. Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age. Cochrane Database Syst Rev. 2011 Sep 7;(9):CD008959. doi: 10.1002/14651858.CD008959.pub2.

  PMID: 21901727 BACKGROUND

• Hotz C, Pelto G, Armar-Klemesu M, Ferguson EF, Chege P, Musinguzi E. Constraints and opportunities for implementing nutrition-specific, agricultural and market-based approaches to improve nutrient intake adequacy among infants and young children in two regions of rural Kenya. Matern Child Nutr. 2015 Dec;11 Suppl 3(Suppl 3):39-54. doi: 10.1111/mcn.12245.

  PMID: 26778801 BACKGROUND

• Inayati DA, Scherbaum V, Purwestri RC, Wirawan NN, Suryantan J, Hartono S, Bloem MA, Pangaribuan RV, Biesalski HK, Hoffmann V, Bellows AC. Combined intensive nutrition education and micronutrient powder supplementation improved nutritional status of mildly wasted children on Nias Island, Indonesia. Asia Pac J Clin Nutr. 2012;21(3):361-73.

  PMID: 22705425 BACKGROUND

• Attanasio OP, Fernandez C, Fitzsimons EO, Grantham-McGregor SM, Meghir C, Rubio-Codina M. Using the infrastructure of a conditional cash transfer program to deliver a scalable integrated early child development program in Colombia: cluster randomized controlled trial. BMJ. 2014 Sep 29;349:g5785. doi: 10.1136/bmj.g5785.

  PMID: 25266222 BACKGROUND

• Andrew A, Attanasio O, Fitzsimons E, Rubio-Codina M. Why is multiple micronutrient powder ineffective at reducing anaemia among 12-24 month olds in Colombia? Evidence from a randomised controlled trial. SSM Popul Health. 2016 Mar 7;2:95-104. doi: 10.1016/j.ssmph.2016.02.004. eCollection 2016 Dec.

  PMID: 29349132 BACKGROUND

• Jack SJ, Ou K, Chea M, Chhin L, Devenish R, Dunbar M, Eang C, Hou K, Ly S, Khin M, Prak S, Reach R, Talukder A, Tokmoh LO, Leon de la Barra S, Hill PC, Herbison P, Gibson RS. Effect of micronutrient sprinkles on reducing anemia: a cluster-randomized effectiveness trial. Arch Pediatr Adolesc Med. 2012 Sep;166(9):842-50. doi: 10.1001/archpediatrics.2012.1003.

  PMID: 22801933 BACKGROUND

• Aboud FE, Akhter S. A cluster-randomized evaluation of a responsive stimulation and feeding intervention in bangladesh. Pediatrics. 2011 May;127(5):e1191-7. doi: 10.1542/peds.2010-2160. Epub 2011 Apr 18.

  PMID: 21502222 BACKGROUND

• Avula R, Frongillo EA, Arabi M, Sharma S, Schultink W. Enhancements to nutrition program in Indian integrated child development services increased growth and energy intake of children. J Nutr. 2011 Apr 1;141(4):680-4. doi: 10.3945/jn.109.116954. Epub 2011 Feb 23.

  PMID: 21346106 BACKGROUND

• Osei AK, Pandey P, Spiro D, Adhikari D, Haselow N, De Morais C, Davis D. Adding multiple micronutrient powders to a homestead food production programme yields marginally significant benefit on anaemia reduction among young children in Nepal. Matern Child Nutr. 2015 Dec;11 Suppl 4(Suppl 4):188-202. doi: 10.1111/mcn.12173.

  PMID: 25682798 BACKGROUND

• Del Castillo SE, Mosquera T, Suárez EL, Heredia P. Nutritional Situation of Rural Communities in Nariño, Colombia 2013. Food and Nutrition Sciences (5): 1521-1528, 2014

  BACKGROUND

Related Links

• Sitio Web. Proyecto Seguridad Alimentaria Nutricional S.A.N. Nariño.

MeSH Terms

Conditions

Anemia

Condition Hierarchy (Ancestors)

Hematologic Diseases; Hemic and Lymphatic Diseases

Study Officials

• Sara E. Del Castillo Matamoros, Professor

  Universidad Nacional de Colombia

  STUDY DIRECTOR

• Javier H. Eslava Schmalbach, Professor

  Universidad Nacional de Colombia

  STUDY DIRECTOR

• Nathalie Ospina Lizarazo, Student

  Universidad Nacional de Colombia

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Master Student

Study Record Dates

• First Submitted: October 9, 2017
• First Posted: October 18, 2017
• Study Start: July 7, 2017
• Primary Completion: November 26, 2017
• Study Completion: November 26, 2017
• Last Updated: October 15, 2018

Record last verified: 2018-10

Locations

CO (1)