NCT03310866

Brief Summary

During fiberoptic endotracheal intubation, the perfect airway exposure produced by the classic curved Macintosh laryngoscope in place of head tilt -chin lift-jaw thrust maneuver may increase the accuracy and produce rapid direct vocal cord access in a short time under Inhalation anesthesia to maintain the respiratory drive for grade III\&VI Modified Mallampati .

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Dec 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 5, 2017

Completed
11 days until next milestone

First Posted

Study publicly available on registry

October 16, 2017

Completed
2 months until next milestone

Study Start

First participant enrolled

December 15, 2017

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 15, 2018

Completed
15 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 30, 2018

Completed
Last Updated

October 5, 2018

Status Verified

October 1, 2018

Enrollment Period

7 months

First QC Date

October 5, 2017

Last Update Submit

October 4, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • intubation time

    time from introduction of the tip of the fiber optic laryngoscope till insertion of the tube in the laryngeal inlet down in the trachea in seconds.

    during intubation

Secondary Outcomes (9)

  • lower jaw relaxation

    during intubation

  • Vocal cord position

    during intubation

  • Neck movements

    during intubation and cuff inflation

  • Cough

    during intubation and cuff inflation

  • 1st trial success rate

    during intubation

  • +4 more secondary outcomes

Study Arms (2)

fiberoptic, airway

ACTIVE COMPARATOR

Classical fiberoptic intubation assisted by side fenestrated airway and head tilt- chin lift- jaw thrust by 2 anesthetist

Device: fiberoptic, airway

fiberoptic, Machintosh

EXPERIMENTAL

oral Fiberoptic bronchoscopic intubation assisted by Macintosh Laryngoscope, by 2 anesthetist

Device: fiberoptic, Machintosh

Interventions

classic fiberoptic bronchoscope, fenstrated airway

fiberoptic, airway

oral fiberoptic brochoscopic, Machintosh laryngoscope

fiberoptic, Machintosh

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult patients with Modified Mallampati (NT-MMT) airway score III,VI
  • American Society of Anaesthesiologists (ASA) physical class I-III
  • Scheduled for elective cancer surgery under general anesthesia

You may not qualify if:

  • Modified Mallampati I,II Airway scored patients.
  • History of upper airway surgery.
  • Patients with serious deformities of the mandible, maxilla, tongue, pharynx or larynx.
  • Patients with a history of significant cardiac and pulmonary diseases,
  • Obesity with BMI \>40,
  • Epilepsy, pregnancy, mental disease, neurological psychological disorders.
  • Communication barrier.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Oncolgy Center, Mansoura University,

Al Mansurah, Dakahlia Governorate, 35516, Egypt

Location

MeSH Terms

Interventions

Optical Fibers

Intervention Hierarchy (Ancestors)

Optical DevicesEquipment and Supplies

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 5, 2017

First Posted

October 16, 2017

Study Start

December 15, 2017

Primary Completion

July 15, 2018

Study Completion

July 30, 2018

Last Updated

October 5, 2018

Record last verified: 2018-10

Data Sharing

IPD Sharing
Will share

after publication

Shared Documents
SAP, CSR
Time Frame
no limit
Access Criteria
e mail mohamed.abdel\ latif@yahoo.com

Locations