NCT03309969

Brief Summary

The aim of this study is to compare intravascular ultrasound with venography in the diagnosis and treatment of iliac vein compression syndrome.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Oct 2017

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 19, 2017

Completed
27 days until next milestone

First Posted

Study publicly available on registry

October 16, 2017

Completed
14 days until next milestone

Study Start

First participant enrolled

October 30, 2017

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2018

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2019

Completed
Last Updated

October 16, 2017

Status Verified

September 1, 2017

Enrollment Period

4 months

First QC Date

September 19, 2017

Last Update Submit

October 13, 2017

Conditions

Outcome Measures

Primary Outcomes (2)

  • Percentage diameter reduction

    Compare the percentage diameter reduction measured by intravascular ultrasound (IVUS) and venography

    1 month

  • Percentage area reduction

    Compare the percentage area reduction measured by IVUS and the calculated percentage area reduction measured by venography

    1 month

Secondary Outcomes (3)

  • CEAP score

    18 months

  • Primary patency

    18 months

  • Secondary patency

    18 months

Study Arms (1)

observation group

Subjects with suspicious iliac vein compression syndrome were included in the observation group.

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Subjects with suspicious iliac vein compression syndrome

You may qualify if:

  • Age: 18 to 90 years
  • Willing to participate in and sign the informed consent
  • Patients with suspicious iliac vein stenosis or compression presented by preoperative magnetic resonance venography (MRV)
  • Patent common femoral vein and/or femoral vein of the study leg
  • Undergoing iliofemoral venography with the intend to treat potential iliac vein compression syndrome

You may not qualify if:

  • Not providing informed consent
  • Venous compression caused by pelvic tumors or fibroid uterus
  • Previous stent implantation or venovenous bypass surgery of the study leg
  • Known metal allergy precluding the possibility of stent implantation
  • Known iodine allergy or severe renal insufficient function which are unsuitable for venography
  • Pregnant or planning to be pregnant recently
  • Acute deep vein thrombosis or tumor thrombus involving the study leg
  • Know history of thrombophilia (e.g. protein C or S deficiency, anti-thrombin III deficiency, etc )
  • Any concurrent disease, for example, heart failure, might make the patients unsuitable for surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

180 Fenglin Road

Shanghai, Shanghai Municipality, 200032, China

RECRUITING

MeSH Terms

Conditions

May-Thurner Syndrome

Condition Hierarchy (Ancestors)

Vascular MalformationsCardiovascular AbnormalitiesCardiovascular DiseasesPeripheral Vascular DiseasesVascular DiseasesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Central Study Contacts

Zhenyu Shi, Doctor

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 19, 2017

First Posted

October 16, 2017

Study Start

October 30, 2017

Primary Completion

March 1, 2018

Study Completion

March 1, 2019

Last Updated

October 16, 2017

Record last verified: 2017-09

Locations