NCT03306966

Brief Summary

The purpose of this observational study is to evaluate the safety and performance of the Single Use Endoscopic Linear Cutter Stapler and Reloads from Frankenman used in (hemi)colectomy to remove tumors and create anastomoses in patients with cancer in the ascending colon. The goal of the study will be achieved by assessing the device performance and reporting of peri- and postoperative complications in a prospectively maintained database.

Trial Health

15
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started May 2018

Typical duration for all trials

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 6, 2017

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 11, 2017

Completed
7 months until next milestone

Study Start

First participant enrolled

May 1, 2018

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2020

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 30, 2021

Completed
Last Updated

June 1, 2018

Status Verified

March 1, 2018

Enrollment Period

2 years

First QC Date

October 6, 2017

Last Update Submit

May 30, 2018

Conditions

Keywords

Ascending colon

Outcome Measures

Primary Outcomes (3)

  • Number of patients with adverse events related to the index-procedure.

    Determination of peri- and postoperative anastomotic leaks and intra-intestinal/intra-abdominal bleeding.

    3 to 4 weeks follow-up

  • Number of patients with adverse events related to the index-procedure.

    Determination of peri- and postoperative anastomotic leaks and intra-intestinal/intra-abdominal bleeding.

    3 months follow-up

  • Number of patients with adverse events related to the index-procedure.

    Determination of peri- and postoperative anastomotic leaks and intra-intestinal/intra-abdominal bleeding.

    6 months follow-up

Secondary Outcomes (9)

  • Number of adverse device effects.

    3 to 4 weeks follow-up

  • Number of adverse device effects.

    3 months follow-up

  • Number of adverse device effects.

    6 months follow-up

  • Number of patients with peri- and early/late postoperative complications related to the open and laparoscopic colectomy.

    3 to 4 weeks follow-up

  • Number of patients with peri- and early/late postoperative complications related to the open and laparoscopic colectomy.

    3 months follow-up

  • +4 more secondary outcomes

Study Arms (1)

Colon cancer patients

Patients with colon cancer (ascending colon) eligible for laparoscopic or open segmental colectomy.

Device: Endoscopic Linear Cutter Stapler and Reloads (Frankenman)

Interventions

The Single Use Endoscopic Linear Cutter Stapler and Reloads from Frankenman received CE-mark in April 2013. It is used to staple and simultaneously divide tissue from the central line.

Colon cancer patients

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with colon cancer (ascending colon) eligible for laparoscopic or open segmental colectomy.

You may qualify if:

  • Age at study entry is at least 18 years.
  • Patient must sign and date the informed consent form prior to the index-procedure.
  • Patient has a tumor in the ascending colon.

You may not qualify if:

  • Patient is pregnant.
  • Patient has inflammatory bowel disease (ulcerative colitis, Crohn's disease).
  • Patient has symptomatic diverticulitis.
  • Patient has bowel trauma.
  • Patient has peritoneal carcinomatosis.
  • Patient is known to be, or suspected of being unable to comply with the study protocol or proposed follow-up visits.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Colonic Neoplasms

Condition Hierarchy (Ancestors)

Colorectal NeoplasmsIntestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal Diseases

Study Officials

  • Kurt Van Der Speeten, Dr

    ZOL, Genk

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
6 Months
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 6, 2017

First Posted

October 11, 2017

Study Start

May 1, 2018

Primary Completion

May 1, 2020

Study Completion

January 30, 2021

Last Updated

June 1, 2018

Record last verified: 2018-03